Ultrasonographic Evaluation of Cholelithiasis with Family History among Adults in Swabi
Article Sidebar
Main Article Content
Abstract
Background: Gallstones, formed within the gallbladder, can lead to serious health complications in adults. Factors such as obesity and age are well-recognized contributors to gallstone formation. However, the influence of family history on the development of cholelithiasis remains unclear.
Objective: This study aims to investigate whether a family history of gallstones increases the likelihood of developing this condition in adults living in Swabi, using ultrasonographic techniques.
Methods: A cross-sectional study was conducted over four months, involving 125 adults diagnosed at Bacha Khan Medical Complex, Swabi, KP, Pakistan. Participants were selected based on a history of cholelithiasis and underwent ultrasonographic examinations using a Toshiba prime machine with convex (3.0—5.0 MHz) and linear (7.0—14.0 MHz) transducers. Family medical history was collected via structured questionnaires. Data were analyzed using SPSS version 25.0, focusing on the prevalence and potential familial ties of gallstone disease.
Results: Of the participants surveyed, 97.7% (n=125) were diagnosed with cholelithiasis, indicating a high prevalence of the condition. Among those with gallstones, 36.2% reported a positive family history, suggesting a significant association between familial history and the occurrence of cholelithiasis.
Conclusion: The study underscores a substantial prevalence of cholelithiasis among adults in Swabi, with a notable association to family history, highlighting the need for further investigation into genetic predispositions and preventive strategies for those at risk.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Ellis HJS. Anatomy of the Gallbladder and Bile Ducts. 2011;29(12):593-6.
Housset C, Chrétien Y, Debray D, Chignard N. Functions of the Gallbladder. 2016;6(3):1549-77.
Schneider G, Grazioli L, Saini S. Imaging of the Biliary Tree and Gallbladder Diseases. In: MRI of the Liver: Imaging Techniques, Contrast Enhancement, Differential Diagnosis. Springer; 2006. p. 237-66.
Beckingham I. Gallstone Disease. 2001;322(7278):91-4.
Venes D. Taber's Cyclopedic Medical Dictionary. FA Davis; 2017.
Devrajani B, Muhammad A, Shah S, Devrajani T, Das T. Frequency of Gallstones in Patients with Diabetes Mellitus: A Hospital-Based Multidisciplinary Study. 2010;16(2):230-2.
Portincasa P, Moschetta A, Palasciano G. Cholesterol Gallstone Disease. 2006;368(9531):230-9.
Cariati A, Cetta F. Rokitansky-Aschoff Sinuses of the Gallbladder Are Associated with Black Pigment Gallstone Formation: A Scanning Electron Microscopy Study. 2003;27(4):265-70.
Sharma H, Gupta G, Sharma MK. Correlation of Gallstone Characteristics with the Clinical Parameters in Cases of Cholelithiasis. Indian J Adv Radiol Surg. 2015;4(3):1-5.
Khalaf SK, Al Mousawi JH. A Study at the Ultrasound Departments of Al-Basrah General Hospital and Al-Fayhaa Hospital in Basrah City, Iraq to Determine the Prevalence of Gallstone. 2023;21-29.
Memon IK, Das B. Gall Stones Through Ultrasonography in Asymptomatic Patients. 2022;6-15.
Zubair M, Javed M. Association of Gallstones with Family History Among Adults. 2022;4-10.
Hashmi FM, Jamil H. Diagnostic Accuracy of Ultrasound in the Diagnosis of Choledocholithiasis. 2022;18-21.
Nasir A, Zulfiqar T. Prevalence of Cholelithiasis Among a General Population in Gujranwala, Punjab, Pakistan. 2022;8-17.
Iqbal Z, Javaid M. Ultrasonographic Incidence of Gallbladder Stones in Individuals with Positive Family History. 2022;12-20.
Farooq M, Batool N. Cholelithiasis in Obese Patients on Grayscale Ultrasonography. 2022;2-9.
Shafique MS, Ahmad R. Frequency and Risk Factors Associated with Gallstone Disease in a Younger Age Group and Possible Complications. 2022;15-23.
Agah S, Fereshtehnejad SM. Epidemiologic Features of Gallstone Disease Among Hospitalized Patients in Rasool-Akram Hospital. 2022;6-14.
Wilson SJ, Thavanathan R, Cheng W, Stuart J, Kim DJ, Glen P, Duigenan S, Shorr R, Woo MM, Perry JJ. Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis. Annals of Emergency Medicine. 2023 Oct 19.
Boitor-Borza D, Rotar IC, Staicu A, Constantin R, Muresan D. Echogenic Content in the Fetal Gallbladder: Systematic Review of Ultrasound Features and Clinical Outcome. Diagnostics. 2023 Jan 8;13(2):230.