Natural Hand Sanitizers: A Systematic Review on the Effectiveness and Antimicrobial Potential Against Pathogens
DOI:
https://doi.org/10.61919/jhrr.v4i3.1131Keywords:
Hand Hygiene, Antimicrobial Activity, Natural Hand SanitizersAbstract
Background: Microbes are mostly transferred through the hands and the nosocomial infections are extremely common. To combat the harmful effects of microbial burden in health care facilities, hand sanitizers are recommended for hand disinfection.
Objective: The goal of this research is to conduct a systematic review of studies on the effectiveness of natural hand sanitizers.
Methods: Under the PRISMA criteria, a systematic search was carried out (Recommended Reporting Items for Systematic Reviews and Meta Analyses) three databases were used to conduct the search: PubMed, Google Scholar, and Science Direct. Published from 2002 to 2024. The Key words for the survey were ‘Natural hand sanitizers, Hand hygiene, Disinfectant, Antibacterial activity. Following the finding of relevant papers, a critical appraisal was carried out in order to select those that would be appropriate for the systematic review. The study's inclusion criteria were surveys, clinical studies, no sample size limits, and only English literature.
Result: The keywords led to the discovery of 65 relevant publications, 14 of which were suitable for the systematic review. Hand sanitizers of several kinds were investigated. It's used to stop the spread of infection and sickness.
Conclusion: In this systematic review, it was concluded that the efficacy and the broad spectrum of natural hand sanitizers were significantly efficient which is important to boost the formulation's effectiveness as well as safety.
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Jing JL, Pei Yi T, Bose RJ, McCarthy JR, Tharmalingam N, Madheswaran T. Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations. Int J Environ Res Public Health. 2020;17(9):3326.
Prajapati P, Desai H, Chandarana C. Hand Sanitizers as a Preventive Measure in COVID-19 Pandemic, Its Characteristics, and Harmful Effects: A Review. J Egypt Public Health Assoc. 2022;97(1):6.
Surwase VB, Savale MM, Jadhav RS, Kadam AB, Shinde PP. Polyherbal Natural Hand Sanitizer Formulation and Evaluation. J Univ Shanghai Sci Technol. 2021;23:932-9.
Chandravanshi JS, Shazia M, Agarwal A, Nandi RG. Formulation of Herbal Hand Sanitizer from Indian Herbs. Lino. 2021;11:1-7.
Gomes M, Zuchi ID, Pavi CP, Fongaro G, da Silva IT, Pezzini BR. Skin-and Eco-Friendly Hand Sanitizer: A Novel Composition of Natural Extracts to Prevent the Spread of Respiratory Viruses. AAPS PharmSciTech. 2024;25(5):98.
Rana A, Mukhia S, Acharya R, Kumar S. Hand Sanitizer With Natural Ingredients Exhibits Enhanced Antimicrobial Efficacy.
Yaun EA, Vasquez BA. Antibacterial Activity of Formulated Psidium Guajava (Guava) Hand Sanitizer Gel on Staphylococcus Aureus. Univ Visayas-J Res. 2017;11(1):1-6.
Aodah AH, Bakr AA, Booq RY, Rahman MJ, Alzahrani DA, Alsulami KA, et al. Preparation and Evaluation of Benzalkonium Chloride Hand Sanitizer as a Potential Alternative for Alcohol-Based Hand Gels. Saudi Pharm J. 2021;29(8):807-14.
Bondurant SW, Duley CM, Harbell JW. Demonstrating the Persistent Antibacterial Efficacy of a Hand Sanitizer Containing Benzalkonium Chloride on Human Skin at 1, 2, and 4 Hours After Application. Am J Infect Control. 2019;47(8):928-32.
Ramesh G, Seth RK, Ramamurthy Sujatha DS. Evaluation of Antibacterial Efficacy of Lemon Grass Oil Eucalyptus Oil and Lemon Juice, as a Hand Sanitizer. Int Ayurvedic Med J. 2011;4:1193-203.
Djima EG, Prasetyaningsih A, Madyaningrana K. Antibacterial Activity of Lime Peel and Lemongrass Extract as Active Ingredients for Spray Hand Sanitizer. SCISCITATIO. 2021;2(1):22-8.
Triastuti A, Sari M, Khasanah N, Chabib L, Fajriyah R, Fitria A. Development of Hand Sanitizer Formulated With Essential Oil From Piper Betle Grown in Yogyakarta, Indonesia. Nveo-Natural Volatiles & Essential Oils J. 2021:12816-27.
Budianti MM. Pengaruh Variasi Konsentrasi Pati Pragelatinisasi Beras Hitam Organik Sebagai Gelling Agent Terhadap Sifat Fisik Sediaan Masker Peel Off Ekstrak Daun Bidara (Ziziphus spina-christi L.).
Abed EH, Shamran DJ, Albakri SA, Mohammed MT, Dhuha JM. Development of Hand Sanitizers Using Teucrium Polium Leaves Extract to Increase the Antimicrobial Efficiency.
Balkrishna A, Singh K, Haldar S, Varshney A. Germi-X Herbal-Based Spray Disinfects Smartphone Surfaces: Implication on Fomite-Mediated Infection Spread. AMB Express. 2022;12(1):30.
Goodarzi A. COVID-19 and Estimate of Antimicrobial Efficacy of Hand Sanitizers. Glob J Pathol Microbiol. 2020;8:6-11.
Surini S, Amirtha NI, Lestari DC. Formulation and Effectiveness of a Hand Sanitizer Gel Produced Using Salam Bark Extract. Int J Appl Pharm. 2018;10:216-20.
Wani NS, Bhalerao AK, Ranaware VP, Rahul Z. Formulation and Evaluation of Herbal Sanitizer. Int J Pharm Tech Res. 2013;5(1):40-3.
Karimie P. Advantages and Disadvantages of Alcohol-Based Hand Sanitizers: A Systematic Review. Turk J Physiother Rehabil. 2021;32:3.
Al-Zahrani SH, Baghdadi AM. Evaluation of the Efficiency of Nonalcoholic-Hand Gel Sanitizers Products as an Antibacterial. Nature Sci. 2012;10(6):15-20.
Herdt BL, Black EP, Zhou SS, Wilde CJ. Inactivation of SARS-CoV-2 by 2 Commercially Available Benzalkonium Chloride-Based Hand Sanitizers in Comparison With an 80% Ethanol-Based Hand Sanitizer. Infect Prev Pract. 2021;3(4):100191.
Hayat A, Munnawar F. Antibacterial Effectiveness of Commercially Available Hand Sanitizers. Int J Biol Biotech. 2016;13(3):427-31.
Malabadi RB, Kolkar KP, Meti NT, Chalannavar RK. Role of Plant-Based Hand Sanitizers During the Recent Outbreak of Coronavirus (SARS-CoV-2) Disease (COVID-19). Significances of Bioengineering & Biosciences. 2021;5(1):458-68.
Srivastava H, Pandey M, Kumar A, Yadav R, Gupta N, Shukla MK. Formulation and Evaluation of Alcohol-Based Herbal Hand Sanitizer.
Ganguly D, Banerjee M, Chakraborty A, Das H, Sekh A, Sarfaraj MA, et al. Preparation and Evaluation of Polyherbal Handwash of Different Herbal Sources. NeuroQuantology. 2022;20(11):8113.
Palmero LC. Development of Aloe Vera Hand Sanitizer. EPRA Int J Multidiscip Res. 2024;10(3):193-8.
Singla D, Saini K. Formulation of an Herbal Substitute for Chemical Sanitizer and Its Evaluation for Antimicrobial Efficiency. Int J Chem Tech Res. 2019;12(3):114-20.
Otokunefor K, Princewill I. Evaluation of Antibacterial Activity of Hand Sanitizers–An in Vitro Study. J Appl Sci Environ Manag. 2017;21(7):1276-80.
Harismah K, Ariningrum ND, Fuadi AM, Mujiburohman M, Mirzaei M. Formulation and Evaluation of Herbal Hand Sanitizer Based on Stevia (Stevia Rebaudiana). J Phys Conf Ser. 2021;1858(1):012053.
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Copyright (c) 2024 Nighat Perveen, Fariha Ibrahim, Asma Ansari
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