Takotsubo Cardiomyopathy: A Case of Young Male with Broken Heart
Takotsubo Cardiomyopathy in Young Male
DOI:
https://doi.org/10.61919/jhrr.v4i3.1223Keywords:
Intubation, Takotsubo Cardiomyopathy (TC), Broken Heart Syndrome , Intubation ComplicationsAbstract
Background: Takotsubo cardiomyopathy (TC), also known as broken heart syndrome, is a transient cardiac condition often triggered by emotional or physical stress. Although predominantly seen in postmenopausal women, this case reports a rare occurrence in a young male following intubation and mechanical ventilation for status asthmaticus.
Objective: To describe a rare case of TC in a young male post-intubation and mechanical ventilation and to emphasize the importance of early diagnosis and appropriate management.
Methods: A 32-year-old male with a history of bronchial asthma was admitted unresponsive, requiring CPR and intubation. Baseline investigations included ECG, cardiac enzymes, echocardiography, and coronary angiography. Data were analyzed descriptively with a focus on clinical presentation, diagnostic findings, and management outcomes.
Results: The patient exhibited ST-segment elevation on ECG and elevated troponin levels (2134.1 ng/L at 12 hours), with echocardiography showing apical hypokinesia. Coronary angiography revealed normal coronary arteries. The patient was successfully weaned from mechanical ventilation on day 3 and showed full recovery with normalization of left ventricular function by discharge.
Conclusion: This case highlights the importance of considering TC in patients with acute coronary syndrome-like symptoms following intubation. Early recognition and management are crucial for favorable outcomes.
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References
Amin HZ, Amin LZ, Pradipta A. Takotsubo Cardiomyopathy: A Brief Review. J Med Life. 2020;13(1):3. doi: 10.25122/jml-2018-0067.
Boyd B, Solh T. Takotsubo Cardiomyopathy: Review of Broken Heart Syndrome. JAAPA. 2020;33(3):24-9. doi: 10.1097/01.JAA.0000654368.35241.fc.
Kariyanna PT, Chandrakumar HP, Jayarangaiah A, Khan A, Vulkanov V, Ashamalla M, et al. Apical Takotsubo Cardiomyopathy in a COVID-19 Patient Presenting With Stroke: A Case Report and Pathophysiologic Insights. Am J Med Case Rep. 2020;8(10):350.
Cau R, Pisu F, Porcu M, Cademartiri F, Montisci R, Bassareo P, et al. Machine Learning Approach in Diagnosing Takotsubo Cardiomyopathy: The Role of the Combined Evaluation of Atrial and Ventricular Strain, and Parametric Mapping. Int J Cardiol. 2023;373:124-33. doi: 10.1016/j.ijcard.2022.11.021.
Brenner B, Corbridge T, Kazzi A. Intubation and Mechanical Ventilation of the Asthmatic Patient in Respiratory Failure. Proc Am Thorac Soc. 2009;6(4):371-9. doi: 10.1513/pats.P09ST4.
Agarwal S, Sanghvi C, Odo N, Castresana MR. Perioperative Takotsubo Cardiomyopathy: Implications for Anesthesiologist. Ann Card Anaesth. 2019;22(3):309. doi: 10.4103/aca.ACA_71_18.
Bairashevskaia AV, Belogubova SY, Kondratiuk MR, Rudnova DS, Sologova SS, Tereshkina OI, et al. Update of Takotsubo Cardiomyopathy: Present Experience and Outlook for the Future. IJC Heart Vasculature. 2022;39:100990. doi: 10.1016/j.ijcha.2022.100990.
Lu X, Li P, Teng C, Cai P, Jin L, Li C, et al. Prognostic Factors of Takotsubo Cardiomyopathy: A Systematic Review. ESC Heart Fail. 2021;8(5):3663-89. doi: 10.1002/ehf2.13531.
Angelini P, Uribe C, Tobis JM. Pathophysiology of Takotsubo Cardiomyopathy: Reopened Debate. Tex Heart Inst J. 2021;48(3). doi: 10.14503/THIJ-20-7490.
Hanif M, Haider MA, Xi Q, Ali MJ, Khan MA. Takotsubo Cardiomyopathy Triggered by the Death of Pets (Cats): Two Case Reports. Cureus. 2020;12(9). doi: 10.7759/cureus.10690.
Laghari AH, Khan AH, Kazmi KA. Takotsubo Cardiomyopathy: Ten Year Experience at a Tertiary Care Hospital in Pakistan. BMC Res Notes. 2014;7:932. doi: 10.1186/1756-0500-7-932.
Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, et al. Contemporary Definitions and Classification of the Cardiomyopathies: An American Heart Association Scientific Statement From the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation. 2006;113(14):1807-16. doi: 10.1161/CIRCULATIONAHA.106.174287.
Madias JE. Left Ventricular Outflow Tract Obstruction/Hypertrophic Cardiomyopathy/Takotsubo Syndrome: A New Hypothesis of Takotsubo Syndrome Pathophysiology. Current Problems in Cardiology. 2024 May 24:102668.
Omiya M, Morii Y, Mukai M, Mitsuhashi Y, Kato K, Isogai T. Myasthenic Crisis and Concomitant Takotsubo Syndrome Complicated by Shock: A Case Report. Internal Medicine. 2024:3306-23.
Muto T, Kyono H. A woman with schizophrenia who died due to Takotsubo cardiomyopathy occurring after electroconvulsive therapy. BMC psychiatry. 2024 Feb 19;24(1):139.
Vu VH, Nguyen TC, Nguyen BT, Tran H, Truong BQ. Clinical characteristics and risk factors of in-hospital mortality in patients with Takotsubo syndrome. MedPharmRes. 2024;8(1):64-73.
AlShehabi N, Hallak Y, Battistin U, Faraji H, Othman M, Alkowatli H, Butt M, Hallak YO. Takotsubo Cardiomyopathy Complicating Diabetic Ketoacidosis, Hypothermia and Hypernatremia in a Comatose Patient. Cureus. 2024 Jul 20;16(7).
Mishra T, Saha R, Paramasivam G. Takotsubo cardiomyopathy in India and its electrocardiography (ECG) comparison to myocardial infarction. The Egyptian Heart Journal. 2024 Feb 21;76(1):26.
Hanif M, Vasigh M, Malik M, Jaiswal V, Shrestha A, Kozman H. Acute myocardial infarction due to coronary artery embolism in atrial fibrillation in Takotsubo cardiomyopathy patient: A case report. Authorea Preprints. 2024 Apr 28.
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Copyright (c) 2024 Amir Rashid, Attia Khaliq, Ayesha Afzal, Karamat Ali, Asad Zaman Khan, Masood Wazir
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