Diabetic Myonecrosis: A Case Report of Acute Muscle Infarction in a Patient with Long-Standing Diabetes Mellitus
Diabetic Myonecrosis in Long-Standing Diabetes
DOI:
https://doi.org/10.61919/jhrr.v4i3.1575Keywords:
Diabetes, complications, necrotizing fasciitis, diabetic myonecrosis.Abstract
Background: Diabetic myonecrosis is a rare complication of long-standing, poorly controlled diabetes mellitus, often associated with microvascular complications and diagnostic challenges. Early recognition and appropriate management are crucial to avoid unnecessary interventions and optimize patient outcomes.
Objective: To report a case of diabetic myonecrosis in a patient with poorly controlled diabetes and highlight its diagnostic approach and management.
Methods: A 49-year-old male with a 30-year history of uncontrolled type 1 diabetes presented with acute pain and swelling in the right thigh. Laboratory investigations included complete blood count, ESR, CRP, and HbA1c. Imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) were used to evaluate muscle involvement. Conservative management included optimized insulin therapy, aspirin, and analgesics.
Results: Laboratory findings showed elevated ESR (121 mm/hr), CRP (3.98 mg/dL), and HbA1c (15.2%). MRI confirmed diffuse muscle edema in the right adductor muscles. Following treatment, pain severity decreased from 8/10 to 2/10, and mobility significantly improved over a two-week period.
Conclusion: Early diagnosis and conservative management of diabetic myonecrosis can prevent complications. Clinicians should consider this condition in patients with acute musculoskeletal pain and poorly controlled diabetes.
Downloads
References
Angervall L, Stener B. Tumoriform Focal Muscular Degeneration in Two Diabetic Patients. Diabetologia. 1965;1:39-42. doi: 10.1007/BF01338714.
Horton WB, Taylor JS, Ragland TJ, Subauste AR. Diabetic Muscle Infarction: A Systematic Review. BMJ Open Diabetes Res Care. 2015;3(1). doi: 10.1136/bmjdrc-2015-000082.
Goswami P, Baruah MP. The Role of MRI in Diagnosis of Diabetic Muscle Infarction: An Underdiagnosed Entity. Int J Endocrinol Metab. 2011;9:353-355.
Choudhury BK, Saikia UK, Sarma D, Saikia M, Choudhury SD, Bhuyan D. Diabetic Myonecrosis: An Underreported Complication of Diabetes Mellitus. Indian J Endocrinol Metab. 2011;15(4):316-318. doi: 10.4103/2230-8210.83343.
Iyer SN, Drake AJ, West RL, Tanenberg RJ. Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus. Case Rep Endocrinol. 2011;2011:407921. doi: 10.1155/2011/407921.
Frank M, Finsterer J. Creatine Kinase Elevation, Lactacidemia, and Metabolic Myopathy in Adult Patients with Diabetes Mellitus. Endocr Pract. 2012;18(3):387-393. doi: 10.4158/EP11316.OR.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Yahya Ur Rehman, Nadia Hashmi, Rabia Umar , Syeda Mubeena Nahri

This work is licensed under a Creative Commons Attribution 4.0 International License.
Public Licensing Terms
This work is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). Under this license:
- You are free to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material) for any purpose, including commercial use.
- Attribution must be given to the original author(s) and source in a manner that is reasonable and does not imply endorsement.
- No additional restrictions may be applied that conflict with the terms of this license.
For more details, visit: https://creativecommons.org/licenses/by/4.0/.