Multidisciplinary Approach Towards Managing Hepatocellular Carcinoma - Experience of a Single Hepatobiliary Center
Multidisciplinary Management of Hepatocellular Carcinoma
DOI:
https://doi.org/10.61919/jhrr.v4i3.1650Keywords:
Hepatocellular carcinoma (HCC), multidisciplinary, managment of HCC, appraoch, TACE, multidisciplinary managmentAbstract
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. A multidisciplinary approach is crucial for optimal management. This study aimed to evaluate the outcomes of HCC patients managed by a multidisciplinary team at a single hepatobiliary center.
Objective: To assess the demographics, clinical characteristics, treatment modalities, and survival outcomes of HCC patients managed with a multidisciplinary approach.
Methods: A retrospective observational study was conducted on 212 HCC patients diagnosed and managed at a tertiary care hospital in Pakistan. Data on demographics, etiology, tumor characteristics, treatment received, and survival were collected and analyzed.
Results: The majority of patients were male (80.7%) with a mean age of 55.96 years. Hepatitis C (66.5%) was the most common risk factor. Most patients presented with intermediate to advanced stage disease (BCLC B: 45%; BCLC C: 24.5%). Transarterial chemoembolization (TACE) was the most frequently used treatment (46.2%). The presence of portal vein thrombosis was significantly associated with mortality (p<0.001).
Conclusion: A multidisciplinary approach is essential for the management of HCC. Early detection and timely intervention are crucial for improved survival.
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Copyright (c) 2024 Sohail Akram, Hira Khalid, Zahoor Muhi-ud-din, Muhammad Imran, Muhammad Fawad, Ali Haider
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