Health Literacy And Treatment Compliance Among Patients With Chronic Kidney Disease Attending A Nephrology Outpatient Department And Dialysis Center In Lahore, Pakistan: An Analytical Cross-Sectional Study

Authors

  • Seerat Fatima Riphah International University Lahore campus, Lahore ,Pakistan.

DOI:

https://doi.org/10.61919/jhrr.v6i6.2017

Keywords:

Chronic kidney disease; health literacy; treatment compliance; treatment adherence; hemodialysis; Pakistan; patient education.

Abstract

Background: Chronic kidney disease (CKD) requires continuous self-management, including medication adherence, dietary and fluid restriction, follow-up care, and dialysis-related practices where applicable. Health literacy may influence patients’ ability to understand CKD-related information and follow treatment recommendations, but local evidence from Pakistan remains limited. Objective: To assess health literacy, CKD awareness, treatment compliance, treatment adherence, and selected clinical burden indicators among dialysis and non-dialysis CKD patients attending nephrology care in Lahore, Pakistan. Methods: A hospital-based analytical cross-sectional study was conducted among 256 adult CKD patients attending the nephrology outpatient department and dialysis center of Sheikh Zayed Hospital, Lahore. Participants were selected using non-probability consecutive sampling. Data were collected through a structured questionnaire/interview covering sociodemographic characteristics, clinical profile, health literacy, treatment compliance, treatment adherence, and barriers to compliance. Descriptive statistics were reported as frequencies and percentages. Results: Among 256 CKD patients, 115 (45.1%) had inadequate health literacy and 129 (50.3%) were unaware of CKD symptoms. Good treatment compliance was observed in 56 patients (21.8%), whereas 200 (78.2%) had poor or suboptimal compliance. Poor treatment adherence was reported in 148 patients (58.0%). Anemia was present in 202 CKD patients (78.7%), while anemia among dialysis patients was reported in 242 patients (94.7%). Six-month mortality was observed in 29 patients (11.4%). Conclusion: CKD patients in this hospital-based population showed substantial gaps in health literacy and CKD awareness, with high frequencies of poor compliance, poor adherence, anemia, and mortality. Structured, culturally appropriate, and family-centered patient education should be integrated into nephrology outpatient and dialysis care. Further inferential analysis using individual-level data is required to confirm the association between health literacy and treatment compliance.

Downloads

Download data is not yet available.

References

Rahmawati B, Rochmawati E. Health literacy in patients undergoing hemodialysis: literature review. Bali Med J. 2022;11(3). doi:10.15562/bmj.v11i3.3754.

Hamza MA, Ullah S, Ahsan H, Ali W, Masud M, Ahmed A. Health literacy, illness perception, and their association with medication adherence in end-stage renal disease. Int Urol Nephrol. 2025. doi:10.1007/s11255-025-04472-8.

Afzal F, Rafique R. Mediating role of self-efficacy between illness perception, health literacy, and treatment adherence among patients undergoing hemodialysis. J Psychol Health Soc Chall. 2026. doi:10.63075/7rqarn67.

Boyer A, Bégin Y, Dupont J, Rousseau-Gagnon M, Fernandez N, Demian M, et al. Health literacy level in a various nephrology population from Québec: predialysis clinic, in-centre hemodialysis and home dialysis; a transversal monocentric observational study. BMC Nephrol. 2021;22. doi:10.1186/s12882-021-02464-1.

Pasari A, Tolani P, Bhawane A, Balwani M. Management of nephrology practice in the environment of poor health literacy: the challenge. J Nephrol Soc. 2022. doi:10.4103/jtns.jtns_11_22.

Zainab R, Arif S, Saddique H, Tasneem S. The assessment of treatment adherence among dialysis patients. Biol Clin Sci Res J. 2024. doi:10.54112/bcsrj.v2024i1.1257.

Bégin Y, Boyer A, Dupont J, Rousseau-Gagnon M, Fernandez N, Demian M, et al. Health literacy level in a various nephrology population: predialysis clinic, in-centre hemodialysis and home dialysis. 2021. doi:10.21203/RS.3.RS-135442/V1.

Boueri M, Abdelkhalik M, Maaz FA, Chehade H, Bouclaous C. Navigating health care in crises: health literacy and treatment adherence among hemodialysis patients in Lebanon. Kidney Med. 2025. doi:10.1016/j.xkme.2025.101081.

Toapanta N, Salas-Gama K, Pantoja PE, Soler MJ. The role of low health literacy in shared treatment decision-making in patients with kidney failure. Clin Kidney J. 2023. doi:10.1093/ckj/sfad061.

Afzal F, Rafique R. A qualitative study on illness perception, health literacy, self-efficacy, and treatment adherence among patients undergoing hemodialysis. J Psychol Health Soc Chall. 2026. doi:10.63075/1fyqah15.

Zahra B, Sagheer M, Ikhtiar R, Attiq S, Lashari A, Shaheen A, et al. Management of patients with dialysis-dependent chronic kidney disease: a prospective observational study at Allama Iqbal Teaching Hospital, Dera Ghazi Khan, Pakistan. J Med Health Sci Rev. 2026. doi:10.65035/g84z0t16.

Butt MN, Zafar U, Ansar F, Butt SN, Basit A, Abrar M, et al. Economic burden and clinical epidemiology of dialysis: a cross-sectional analysis of chronic kidney disease patients. Cureus. 2025. doi:10.7759/cureus.93372.

Kazmi SMK, Rabab UE, Dawood T, Arif S, Azam SM, Bokhari SMNA, et al. Assessment of knowledge, attitudes, and practices associated with chronic kidney disease in Pakistan. Eur J Health Sci. 2023. doi:10.47672/ejhs.1696.

Rizzolo K, Al-Rousan T, Cervantes L. Dialysis decision making and the patient experience: lessons from Pakistan. Kidney Med. 2022;4(11):100556. doi:10.1016/j.xkme.2022.100556.

Dhania B, Kumar A, Kalal N, Bajpai NK. Burden and treatment seeking behaviour in chronic kidney disease patients: a cross-sectional descriptive study. Int J Community Med Public Health. 2021;8(10):4976. doi:10.18203/2394-6040.ijcmph20213805.

Billany R, Thopte A, Adenwalla SF, March D, Burton J, Graham-Brown M. Associations of health literacy with self-management behaviours and health outcomes in chronic kidney disease: a systematic review. J Nephrol. 2023. doi:10.1007/s40620-022-01537-0.

Khan A, Hussain SG, Mushtaq S, Abbas S, Dong Y, Feng W, et al. Prevalence and management of anemia and impact of treatment burden on health-related quality of life in chronic kidney disease and dialysis patients. J Pharm Policy Pract. 2024. doi:10.1080/20523211.2024.2427779.

Ahmed J, Azhar S, Haq NU, Hussain S, Stájer A, Urbán E, et al. Awareness of chronic kidney disease, medication, and laboratory investigation among nephrology and urology patients of Quetta, Pakistan. Int J Environ Res Public Health. 2022;19(9):5015. doi:10.3390/ijerph19095015.

Ahmad W. Retrospective evaluation of a large nephrology out-patient cohort. Pak J Kidney Dis. 2025;9(1):54-57. doi:10.53778/pjkd91294.

Hussain F, Ashraf S, Arshad M, Rehman MAU, Khan F, Ahmad MA, et al. Knowledge, adherence, and perception of patients on maintenance hemodialysis to treatment regimens at a tertiary care hospital in Pakistan. Cureus. 2023. doi:10.7759/cureus.51341.

Downloads

Published

2026-06-30

How to Cite

Fatima, S. (2026). Health Literacy And Treatment Compliance Among Patients With Chronic Kidney Disease Attending A Nephrology Outpatient Department And Dialysis Center In Lahore, Pakistan: An Analytical Cross-Sectional Study. Journal of Health and Rehabilitation Research, 6(6). https://doi.org/10.61919/jhrr.v6i6.2017

Issue

Section

Articles