Nurses' Knowledge and Practices Regarding Safe Handling of Chemotherapeutic Agents Safe Handling of Chemotherapeutic Agents
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Abstract
Background: Chemotherapy agents are highly toxic and pose health risks not only to patients but also to healthcare providers, particularly nurses who handle these agents frequently. Safe handling practices are essential to protect both patients and healthcare staff from potential hazards.
Objective: To assess the knowledge and practices of nurses regarding the safe handling of chemotherapeutic agents.
Methods: A cross-sectional study was conducted in oncology units across five hospitals in Peshawar, Khyber Pakhtunkhwa, with 250 nurses sampled through proportionate sampling. Data were collected using an adapted questionnaire from Asefa et al. (17), comprising socio-demographic data and questions on safe handling practices. Ethical approval was granted by Bacha Khan University’s Ethical Review Board, and data analysis was conducted with SPSS version 25.
Results: The mean age of participants was 35.56 years; 89% were female, and 76% held a diploma in nursing. Knowledge levels were low, with 70% displaying poor knowledge, 20% moderate, and 10% good. Practice levels were unsatisfactory in 75% of cases, with only 25% demonstrating satisfactory practices.
Conclusion: Significant gaps exist in nurses' knowledge and practices regarding chemotherapy handling. Targeted training and strict adherence to safety protocols are essential to improve these outcomes.
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References
Berlanga P, Vicente ML, Cañete A, Alberich C, Castel V. Cancer In Children And Adolescents In Spain: Incidence, Treatment Setting And Provider Specialty. Clin Transl Oncol. 2016;18(1):27–32.
Shamsi A, Azizzadeh Forouzi M, Iranmanesh S. Psychosocial Risks Among Parents Of Children With Cancer. J Pediatr Nurs. 2016;2(3):44–55.
Siegel RL, Miller KD, Jemal A. Cancer Statistics, 2020. CA Cancer J Clin. 2020;70(1):7–30.
Mirzadeh M, Mirzaei M, ShogaeiFar H. Years Of Life Lost And Childhood And Adolescent Cancer Mortality In Yazd Province, Iran (2004-2009). Iran J Pediatr Hematol Oncol. 2015;5(3):125–30.
Sattar S, Alibhai SMH, Fitch M, Krzyzanowska M, Leighl N, Puts MTE. Chemotherapy And Radiation Treatment Decision-Making Experiences Of Older Adults With Cancer: A Qualitative Study. J Geriatr Oncol. 2018;9(1):47–52.
Huang CY, Ju DT, Chang CF, Muralidhar Reddy P, Velmurugan BK. A Review On The Effects Of Current Chemotherapy Drugs And Natural Agents In Treating Non-Small Cell Lung Cancer. Biomed. 2017;7(4):12–23.
Lennan E, Roe H. Role Of Nurses In The Assessment And Management Of Chemotherapy-Related Side Effects In Cancer Patients. Nurs Res Rev. 2018;2(3):103–11.
Fonseca TG, Auguste M, Ribeiro F, Cardoso C, Mestre NC, Abessa DMS, et al. Environmental Relevant Levels Of The Cytotoxic Drug Cyclophosphamide Produce Harmful Effects In The Polychaete Nereis Diversicolor. Sci Total Environ. 2018;636:798–809.
Schirrmacher V. From Chemotherapy To Biological Therapy: A Review Of Novel Concepts To Reduce The Side Effects Of Systemic Cancer Treatment. Int J Oncol. 2019;54(2):407–19.
Nejat N, Mehrabi F. The Occupational Hazards Of Exposure To Antineoplastic And Chemotherapy Drugs In Nurses: A Systematic Review. Ijcair. 2020;1(3):20–8.
Sasaki M, Ishii N, Kikuchi Y, Kudoh Y, Sugiyama R, Hasebe M. Occupational Exposures Among Nurses Caring For Chemotherapy Patients: Quantitative Analysis Of Cyclophosphamide And Α-Fluoro-Β-Alanine In Urine. Sangyo Eiseigaku Zasshi. 2018;58(5):164–72.
Momeni M, Askarian M, Azad H, Danaei M. Exposure To Cytotoxic Drugs Threatens The Health Of Staff In Oncology Wards. Russ Open Med J. 2021;10(3):318.
Maggen C, Wolters Vera, Van Calsteren K, Cardonick E, Laenen A, Heimovaara JH, et al. Impact Of Chemotherapy During Pregnancy On Fetal Growth. J Matern Neonatal Med. 2022;1–11.
Elsharkawy A, Abouheiba M. Home Safety Precautions The Week After Administration Of Chemotherapy For Children. Egypt J Heal Care. 2021;12(3):240–59.
Simegn W, Dagnew B, Dagne H. Knowledge And Associated Factors Towards Cytotoxic Drug Handling Among University Of Gondar Comprehensive Specialized Hospital Health Professionals: Institutional-Based Cross-Sectional Study. Environ Health Prev Med. 2020;25(1):11.
Komatsu H, Yagasaki K, Yoshimura K. Current Nursing Practice For Patients On Oral Chemotherapy: A Multicenter Survey In Japan. BMC Res Notes. 2014;7(1):1–8.
Asefa S, Aga F, Dinegde NG, Demie TG. Knowledge And Practices On The Safe Handling Of Cytotoxic Drugs Among Oncology Nurses Working At Tertiary Teaching Hospitals In Addis Ababa, Ethiopia. Drug Healthc Patient Saf. 2021;13:71–80.
Azodo CC, Omuemu VO. Perception Of Spirituality, Spiritual Care, And Barriers To The Provision Of Spiritual Care Among Undergraduate Nurses In The University Of Lagos, Nigeria. J Clin Sci. 2017;14(1):119–25.
Hosen MS, Hasan M, Saiful Islam M, Raseduzzaman MM, Tanvirul Islam M, Tazbiul Islam M, et al. Evaluation Of Knowledge And Practice Of Handling Chemotherapy Agents By Nurses: A Multi-Centre Study In Bangladesh. Int J Community Med Public Health. 2019;6(10):4175–80.
Choudhary VS. Assessment Of The Knowledge And Attitudes Of Staff Nurses On Nursing Care Of Cancer Patients Undergoing Chemotherapy At Selected Cancer Hospitals Of Punjab. Nurs Care Open Access J. 2016;1(2):18–24.
Shrestha D, Lama S, Badu A, Mandal GN. Impact Of Educational Intervention. Health Renaiss. 2019;13(1):13–22.
Von Grünigen S, Geissbühler A, Bonnabry P. The Safe Handling Of Chemotherapy Drugs In Low- And Middle-Income Countries: An Overview Of Practices. J Oncol Pharm Pract. 2022;28(2):410–20.
Boiano JM, Steege AL, Sweeney MH. Adherence To Safe Handling Guidelines By Healthcare Workers Who Administer Antineoplastic Drugs. J Occup Environ Hyg. 2016;11(11):728–40.
Kalogianni KG, Mohsen MM, Fareed ME. Chemotherapy Safety Protocol For Oncology Nurses: Its Effect On Their Protective Measures Practices. Int J Med Health Pharm Biomed Eng. 2017;7(9):45–56.
Al-Attar WMA, Hassain A, Al-Gannem M. Effectiveness Of The Nursing Educational Program Upon Nurses' Knowledge And Practices Concerning Chemotherapy Precautions. IOSR J Nurs Health Sci. 2015;4(6):2320–1940.