Enhancing Human Wellbeing through Nutrient-Rich Supplements: The Synergistic Effects of Selenium Nanoparticles and Prosopis Cineraria on Antioxidant Capacity and Overall Health
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Abstract
Background: Nutrient-rich supplements can enhance human health and well-being through improved antioxidant capacity. Selenium nanoparticles (SeNPs) and Prosopis cineraria (PC) are known for their individual health benefits, including antioxidant and anti-inflammatory properties.
Objective: This study investigated the synergistic effects of SeNPs and PC supplementation on antioxidant enzyme activities, lipid profiles, and overall health outcomes in humans.
Methods: Participants were divided into four groups: Control, SeNPs, PC, and SeNPs + PC. Blood samples and surveys were collected over an eight-week supplementation period. The antioxidant enzyme activities were measured using commercial assay kits for superoxide dismutase, catalase, and glutathione peroxidase. Lipid profiles, including omega-3 and saturated fatty acids, were analyzed through gas chromatography. Self-reported health outcomes were assessed via standardized surveys. Statistical analysis was performed using SPSS version 25, with ANOVA and Tukey's post-hoc tests determining significant differences among groups.
Results: The SeNPs + PC group showed a significant increase in superoxide dismutase (30.2 U/mg), catalase (15.8 U/mg), and glutathione peroxidase (21.3 U/mg) activities compared to other groups. Omega-3 fatty acids increased to 0.65 mg/g, while saturated fatty acids decreased to 0.67 mg/g. Participants reported improved energy levels and cognitive function.
Conclusion: SeNPs and PC synergistically improve antioxidant defenses, lipid profiles, and overall health outcomes, suggesting their potential as effective supplements for enhancing human well-being.
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