Assessment of Medication Adherence and Its Association with Health Literacy Among Hypertensive Patients
Medication Adherence and Health Literacy in Hypertension
DOI:
https://doi.org/10.61919/jhrr.v4i3.1554Keywords:
hypertension, antihypertensive medication, medication adherence, health literacy, healthcare compliance, patient education, public health, chronic disease management.Abstract
Background: Hypertension management relies heavily on medication adherence, which is influenced by health literacy. Inadequate adherence can lead to complications, including cardiovascular diseases and stroke.
Objective: To assess the frequency of adherence to antihypertensive medication and its association with health literacy.
Methods: A cross-sectional study was conducted at the University of Lahore Teaching Hospital, involving 375 hypertensive patients aged 18 to 80 years. Medication adherence was evaluated using the Morisky Levine Green questionnaire, and health literacy was assessed using the Single Item Literacy Screener (SILS). Chi-square statistics were employed to determine the association between adherence and health literacy. Data was analyzed using SPSS version 26, with p-value ≤ 0.05 considered statistically significant.
Results: Out of 375 participants, 244 (65.1%) were adherent to medication. Among those with inadequate health literacy (n = 177), only 79 (32.4%) adhered to their medication, while 165 (67.6%) of those with adequate health literacy were adherent. A significant association was found between health literacy and medication adherence (p < 0.001).
Conclusion: Non-adherence to antihypertensive treatment is significantly associated with inadequate health literacy. Educational interventions are necessary to improve adherence and patient outcomes.
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References
Bakris G, Ali W, Parati G. ACC/AHA versus ESC/ESH on hypertension guidelines: JACC guideline comparison. J Am Coll Cardiol. 2019;73(23):3018-26.
Arnett DK, Blumenthal RS, Albert MA, Buroker AB, Goldberger ZD, Hahn EJ, et al. 2019 ACC/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;140(11):e596-e646.
Mills KT, Stefanescu A, He J. The global epidemiology of hypertension. Nat Rev Nephrol. 2020;16(4):223-37.
Riaz M, Shah G, Asif M, Shah A, Adhikari K, Abu-Shaheen A. Factors associated with hypertension in Pakistan: A systematic review and meta-analysis. PloS one. 2021;16(1):e0246085.
Song J-J, Ma Z, Wang J, Chen L-X, Zhong J-C. Gender differences in hypertension. J Cardiovasc Transl Res. 2020;13:47-54.
Mubarik S, Malik SS, Mubarak R, Gilani M, Masood N. Hypertension associated risk factors in Pakistan: A multifactorial case-control study. J Pak Med Assoc. 2019;69(8):1070-3.
Kifle ZD, Adugna M, Chanie GS, Mohammed A. Prevalence and associated factors of hypertension complications among hypertensive patients at University of Gondar Comprehensive Specialized Referral Hospital. Clin Epidemiol Glob Health. 2022;13:100951.
Saqlain M, Riaz A, Malik MN, Khan S, Ahmed A, Kamran S, et al. Medication adherence and its association with health literacy and performance in activities of daily livings among elderly hypertensive patients in Islamabad, Pakistan. Medicina. 2019;55(5):163.
Lor M, Koleck TA, Bakken S, Yoon S, Dunn Navarra A-M. Association between health literacy and medication adherence among hispanics with hypertension. J Racial Ethn Health Disparities. 2019;6:517-24.
Algabbani FM, Algabbani AM. Treatment adherence among patients with hypertension: findings from a cross-sectional study. Clin Hypertens. 2020;26:18.
Noreen N, Bashir F, Khan AW, Safi MM, Lashari WA, Hering D. Determinants of Adherence to Antihypertension Medications Among Patients at a Tertiary Care Hospital in Islamabad, Pakistan, 2019. Prev Chronic Dis. 2023;20:E42.
Mirzaei M, Mirzaei M, Bagheri B, Dehghani A. Awareness, treatment, and control of hypertension and related factors in adult Iranian population. BMC Public Health. 2020;20(1):667.
Wibowo MINA, Yasin NM, Kristina SA, Prabandari YS. A systematic review on self-reported questionnaires to assess medication adherence in diabetic patients. Malaysian J Public Health Med. 2021;21(2):359-73.
Shea JA, Beers BB, McDonald VJ, Quistberg DA, Ravenell KL, Asch DA. Assessing health literacy in African American and Caucasian adults: disparities in rapid estimate of adult literacy in medicine (REALM) scores. Fam Med. 2004;36(8):575-81.
Carey RM, Wright JT, Jr., Taler SJ, Whelton PK. Guideline-Driven Management of Hypertension: An Evidence-Based Update. Circulation research. 2021;128(7):827-46.
Malih Radhi M, Zair Balat K. Health Literacy and Its Association With Medication Adherence in Patients With Hypertension: A Mediating Role of Social Support. Iran Rehab J. 2024;22(1):117-28.
Ferreira PD, Jr., Simoes JA, Sr., Velho DC, Sr. Adherence to Antihypertensive Therapy and Its Determinants: A Systematic Review. Cureus. 2024;16(5):e59532.
Kilic HF, Dag S, MSc S. The relationship between health literacy and medication adherence in a hypertensive patient population. Int J Caring Sci. 2020;13(1):101-7.
Tola Gemeda A, Regassa LD, Weldesenbet AB, Merga BT, Legesse N, Tusa BS. Adherence to antihypertensive medications and associated factors among hypertensive patients in Ethiopia: Systematic review and meta-analysis. SAGE open medicine. 2020;8:2050312120982459.
Guerra C, Conte E, Del Rio AI, Motta J, Moreno Velasquez I, Quintana HK. Medication adherence in hypertensive individuals in Panama 2019: a national cross-sectional study. Healthcare. 2022;10(11):2244.
Andala S, Sofyan H, Hasballah K, Marthoenis. Knowledge and acceptance associated with medication adherence among hypertension individuals in Aceh province, Indonesia. Heliyon. 2024;10(7):e29303.
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