Comparison of Antimicrobial Effecte of Tiple Antibioic Paste and Calcium Treatment of Apical Periodontitis of Permanent Teeth

Authors

  • Sangeen Ameer Operative Dentistry Department, Sandeman Provincial Hospital/Bolan Medical College, Quetta, Pakistan
  • Syed Attaullah Shah Operative Dentistry Department, Sandeman Provincial Hospital, Quetta, Pakistan
  • Farhat Fatima Operative Dentistry Department, Sandeman Provincial Hospital, Quetta, Pakistan
  • Sadia Malik Operative Dentistry Department, Sandeman Provincial Hospital, Quetta, Pakistan
  • Shazmeem Alim Operative Dentistry Department, Sandeman Provincial Hospital/Bolan Medical College, Quetta, Pakistan
  • Sana Kanwal Operative Dentistry Department, Sandeman Provincial Hospital/Bolan Medical College, Quetta, Pakistan

DOI:

https://doi.org/10.61919/jhrr.v3i2.786

Keywords:

Propolis, Triple antibiotic paste, Regenerative endodontics, Intracanal medicaments, Immature permanent teeth

Abstract

Background: Immature permanent teeth with necrotic pulps and open apices present challenges in endodontic management due to thin dentinal walls, lack of apical constriction, and risk of fracture. Triple antibiotic paste (TAP) is widely used in regenerative endodontic therapy, but its drawbacks include potential discoloration, cytotoxicity, and antibiotic resistance. Propolis, a natural resinous product rich in flavonoids, exhibits broad-spectrum antimicrobial properties and favorable biocompatibility, making it a potential alternative. Objective: To compare the antimicrobial efficacy of TAP and propolis as intracanal medicaments in immature permanent teeth with apical periodontitis. Methods: In this single-blinded randomized clinical trial, 30 single-rooted non-vital immature permanent teeth from patients aged 7–14 years were allocated to receive TAP or propolis after irrigation with 1.5% sodium hypochlorite. Microbiological samples were collected at baseline (S1), post-irrigation (S2), and post-medication after 3–4 weeks (S3). Bacterial counts (CFU/mL) were compared using Friedman and Mann–Whitney U tests. Results: Both groups showed significant reductions from S1 to S3 (TAP p=0.008; propolis p=0.004). Between-group differences at all timepoints and in net reduction were not statistically significant. Propolis maintained a consistent decline, whereas TAP showed a modest rebound at S3. Conclusion: Propolis demonstrated antimicrobial efficacy comparable to TAP, supporting its use as a natural alternative in regenerative endodontics.

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References

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Published

2023-08-22

How to Cite

Sangeen Ameer, Syed Attaullah Shah, Farhat Fatima, Sadia Malik, Shazmeem Alim, & Sana Kanwal. (2023). Comparison of Antimicrobial Effecte of Tiple Antibioic Paste and Calcium Treatment of Apical Periodontitis of Permanent Teeth. Journal of Health and Rehabilitation Research, 3(2), 1–6. https://doi.org/10.61919/jhrr.v3i2.786

Issue

Vol. 3 No. 2 (2023): Volume 3, Issue 2 - July to December 2023

Section

Articles

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Copyright (c) 2023 Sangeen Ameer, Syed Attaullah Shah, Farhat Fatima, Sadia Malik, Shazmeem Alim, Sana Kanwal

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