Role of Ovarian Volume in Fertile and Infertile Women by Sonography at Swabi
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Abstract
Background: The measurement of ovarian volume via sonography is an important parameter in assessing ovarian aging and defining fertility potential in women. In the Swabi region, where advanced medical facilities are limited, measuring ovarian volume could be particularly useful for diagnosing fertility issues. This cross-sectional study investigates the relationship between ovarian size and female fertility among women in Swabi.
Objective: To evaluate the role of ovarian volume in distinguishing between fertile and infertile women in the Swabi district using ultrasound.
Methods: A cross-sectional study was conducted at the Department of Radiology, Mahaban Medical and Research Hospital, Swabi, Khyber-Pakhtunkhwa, Pakistan. A total of 101 participants were recruited from community health clinics using convenience sampling. Data on demographic characteristics, medical history, and menstrual cycle regularity were collected via standardized questionnaires. Ovarian dimensions were measured by trained personnel using transvaginal sonography (TVUS), which provided accurate and reproducible results. Descriptive statistics, including means, standard deviations, and percentages, were calculated for variables such as age, ovarian measurements, and fertility status. Cross-tabulation was used to classify participants based on fertility status and menstrual cycle regularity. Correlation tables were generated to examine the interrelationship between fertility status and cycle regularity. Data analysis was performed using the Statistical Software for Social Sciences (SPSS version 25.0).
Results: The average age of participants was 28.52 years (SD = 5.08). The mean ovarian volumes for the right and left ovaries were 6.66 cm³ (SD = 3.28) and 7.46 cm³ (SD = 4.26), respectively. Among the participants, 62 were fertile, and 39 were infertile. Fertile participants had slightly higher mean ovarian measurements (right ovary: 6.90 cm³, left ovary: 7.19 cm³) compared to infertile participants (right ovary: 6.29 cm³, left ovary: 7.89 cm³). The regularity of menstrual cycles did not significantly differ between fertile and infertile women, with 31 fertile participants having regular cycles and 31 having irregular cycles.
Conclusion: The study found that fertile women had slightly higher ovarian volumes compared to infertile women. However, menstrual cycle regularity did not differ significantly between the two groups. These findings suggest that while ovarian volume may be a useful indicator of fertility, menstrual cycle regularity alone is not a reliable predictor of fertility status in this cohort.
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References
Kelsey TW, Dodwell SK, Wilkinson AG, Greve T, Andersen CY, Anderson RA, et al. Ovarian Volume Throughout Life: A Validated Normative Model. PLoS One. 2013;8(9).
Van Voorhis BJ. Ultrasound Assessment Of The Ovary In The Infertile Woman. Semin Reprod Med. 2008;26(3):217-22.
Wallace WH, Kelsey TW. Ovarian Reserve And Reproductive Age May Be Determined From Measurement Of Ovarian Volume By Transvaginal Sonography. Hum Reprod. 2004;19(7):1612-7.
Zaidi S, Usmani A, Shokh IS, Alam SE. Ovarian Reserve And BMI Between Fertile And Subfertile Women. J Coll Physicians Surg Pak. 2009;19(1):21-4.
Lass A, Brinsden PJ. The Role Of Ovarian Volume In Reproductive Medicine. Hum Reprod Update. 1999;5(3):256-66.
Yunus S, Rasheed S, Amanullah A, Aman S, Ullah U, Wazir FU. Ovarian Volume Between Fertile And Infertile Married Women With Transvaginal Sonography. Gomal J Med Sci. 2018;16(4):101-4.
Kanwal HI, Shahid M, Bacha RJ. Sonographic Evaluation Of Various Causes Of Female Infertility: A Literature Review. J Dow Univ Health Sci. 2022;38(2):155-9.
Sharara FI, McClamrock HD. The Effect Of Aging On Ovarian Volume Measurements In Infertile Women. Obstet Gynecol. 1999;94(1):57-60.
Jamil AT, Gilani SA, Malik SS, Bacha R, Yasir S. Diagnostic Accuracy Of Transabdominal Versus Transvaginal Sonography In The Detection Of Polycystic Ovaries Taking Transvaginal Sonography As Gold Standard In Islamabad Population. J Soc Obstet Gynaecol Pak. 2019;9(1):51-5.
Usmani A, Shokh IS, Alam SE. Examination Of Ovarian Reserve In Fertile Women Using Ultrasonography. J Coll Physicians Surg Pak. 2008;18(1):21-4.
Anjum S, Shokh IS, Alam SE. Research On Ovarian Reserve Parameters And Response To Controlled Ovarian Stimulation In Infertile Patients. J Coll Physicians Surg Pak. 2019;29(3):173-7.
Ng EHY, Yeung WSB, Fok ACY, Ho PC. Effects Of Age On Hormonal And Ultrasound Markers Of Ovarian Reserve In Chinese Women With Proven Fertility. Hum Reprod. 2000;15(6):1293-8.
Ezzat RS, Abdallah W, Elsayed M, Saleh HS, Abdalla W. Impact of bariatric surgery on androgen profile and ovarian volume in obese polycystic ovary syndrome patients with infertility. Saudi journal of biological sciences. 2021 Sep 1;28(9):5048-52.
Penzias A, Azziz R, Bendikson K, Cedars M, Falcone T, Hansen K, Hill M, Jindal S, Kalra S, Mersereau J, Racowsky C. Fertility evaluation of infertile women: a committee opinion. Fertility and sterility. 2021 Nov 1;116(5):1255-65.
Lunding SA, Pors SE, Kristensen SG, Bøtkjær JA, Ramløse M, Jeppesen JV, Flachs EM, Pinborg A, Macklon KT, Pedersen AT, Andersen CY. Ovarian cortical follicle density in infertile women with low anti-Müllerian hormone. Journal of assisted reproduction and genetics. 2020 Jan;37:109-17.
Naumova I, Castelo-Branco C, Kasterina I, Casals G. Quality of life in infertile women with polycystic ovary syndrome: a comparative study. Reproductive Sciences. 2021 Jul;28(7):1901-9.
Björvang RD, Hassan J, Stefopoulou M, Gemzell-Danielsson K, Pedrelli M, Kiviranta H, Rantakokko P, Ruokojärvi P, Lindh CH, Acharya G, Damdimopoulou P. Persistent organic pollutants and the size of ovarian reserve in reproductive-aged women. Environment International. 2021 Oct 1;155:106589.
Wu J, Zhao YJ, Wang M, Tang MQ, Liu YF. Correlation analysis between ovarian reserve and thyroid hormone levels in infertile women of reproductive age. Frontiers in Endocrinology. 2021 Sep 27;12:745199.
Siristatidis C, Pouliakis A, Sergentanis TN. Special characteristics, reproductive, and clinical profile of women with unexplained infertility versus other causes of infertility: a comparative study. Journal of Assisted Reproduction and Genetics. 2020 Aug;37(8):1923-30.
Cedars MI. Evaluation of female fertility—AMH and ovarian reserve testing. The Journal of Clinical Endocrinology & Metabolism. 2022 Jun 1;107(6):1510-9.