Optimizing Blood Management: A Comprehensive Study on Blood Transfusion Practices and Wastage Reduction Strategies at Tertiary Care Hospital

Optimization of Blood Transfusion Practices

Authors

  • Maryam Khalid Isra University Islamabad Pakistan https://orcid.org/0009-0007-3894-8672
  • Muhammad Nadeem Khalid Isra University Islamabad Pakistan
  • Farya Sadiq Isra University Islamabad Pakistan
  • Mohsan Aslam Isra University Islamabad Pakistan
  • Shahzeera Begum Isra University Islamabad Pakistan
  • Usama Khalil Qadri Shaheed Zulfiqar Ali Bhutto Medical University (SZABMU) Islamabad Pakistan
  • Mahe-Kamil Qureshi Hashmi Isra University Islamabad Pakistan
  • Shamshad Kousar Chaudhary Isra University Islamabad Pakistan
  • Rehmatullah Zadran National Infectious Disease Laboratory Kabul Afghanistan.
  • Umer Ali Isra University Islamabad Pakistan

DOI:

https://doi.org/10.61919/jhrr.v4i3.1142

Keywords:

Blood wastage, blood components, blood bank, discard rates, resource utilization

Abstract

Background: Blood transfusion is a vital medical intervention used to treat various conditions worldwide. However, many healthcare facilities, including tertiary care hospitals, face challenges in managing blood supplies efficiently, resulting in significant wastage. This study focuses on evaluating blood wastage at a tertiary care hospital's blood bank and identifying the factors contributing to this issue.

Objective: The study aimed to assess the extent and reasons for the wastage of whole blood and its components at a tertiary care hospital's blood bank and propose strategies for improvement.

Methods: Conducted at the Institute of Medical Lab Technology, Isra University Islamabad, this cross-sectional study employed retrospective data collection from September 30th to December 31st, 2023. A sample of 14,261 blood donations was analyzed using SPSS Version 25 to identify donation patterns, donor demographics, blood group distribution, virus screening outcomes, and discard reasons. The study adhered to ethical standards per the Declaration of Helsinki, with informed consent obtained from all participants.

Results: Out of 14,261 donations, 613 units (4.29%) were discarded. Male donors comprised 99.52% of the sample, with the 26-35 age group contributing 41.83% of donations. Blood group B (Positive) accounted for 31.56% of donations. Common discard reasons included low volume (2.17%) and lipemic samples (0.74%).

Conclusion: The study highlighted significant gender disparities and identified key factors contributing to blood wastage. Implementing targeted strategies to enhance donor recruitment and improve blood management practices can optimize resource utilization and enhance patient care.

Downloads

Download data is not yet available.

Author Biographies

Maryam Khalid, Isra University Islamabad Pakistan

Department of Medical Lab Technology, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

Muhammad Nadeem Khalid, Isra University Islamabad Pakistan

Department of Medical Lab Technology, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

Farya Sadiq, Isra University Islamabad Pakistan

Department of Medical Lab Technology, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

Mohsan Aslam, Isra University Islamabad Pakistan

Department of Medical Lab Technology, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

Shahzeera Begum, Isra University Islamabad Pakistan

Department of Medical Lab Technology, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

Usama Khalil Qadri, Shaheed Zulfiqar Ali Bhutto Medical University (SZABMU) Islamabad Pakistan

Department of Molecular Biology, Shaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan

Mahe-Kamil Qureshi Hashmi, Isra University Islamabad Pakistan

Department of Nursing, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

Shamshad Kousar Chaudhary, Isra University Islamabad Pakistan

Department of Nursing, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

Rehmatullah Zadran, National Infectious Disease Laboratory Kabul Afghanistan.

WHO-Surveillance Department, National Infectious Disease Laboratory, Kabul, Afghanistan.

Umer Ali, Isra University Islamabad Pakistan

Department of Medical Lab Technology, Al Nafees Medical College and Hospital, Isra University Islamabad, Pakistan

References

Javid A, Jalali Z, Klassen KJ. Outpatient Appointment Systems in Healthcare: A Review of Optimisation Studies. Eur J Oper Res. 2023;258(1):3–34.

Alfonso E, Augusto V, Xie X. Mathematical Programming Models for Annual and Weekly Bloodmobile Collection Planning. IEEE Trans Autom Sci Eng. 2022;12(1):96–105.

Alfonso E, Xie V, Augusto O, Garraud O. Modeling and Simulation of Blood Collection Systems. Health Care Manag Sci. 2021;15(1):63–78.

Alhammadi JA, Romagnoli J. Process Design and Operation: Incorporating Environmental, Profitability, Heat Integration, and Controllability Considerations. Comput Aided Chem Eng. 2021;17:264–305.

Arvan M, Moghaddam RT, Abdollahi M. Designing a Bi-Objective, Multi-Product Supply Chain Network for Blood Supply. Uncertain Supply Chain Manag. 2022;3(1):57–68.

Attari MYN, Pasandideh SHR, Aghaie A, Niaki STA. A Bi-Objective Robust Optimization Model for a Blood Collection and Testing Problem: An Accelerated Stochastic Benders Decomposition. Ann Oper Res. 2023;1–3. DOI:10.1007/s10479-018-3059-9.

Ayer T, Zhang C, Zeng C. Analysis and Improvement of Blood Collection Operations. Manuf Serv Oper Manag. 2023;21(1):29–46.

Ba S, Gure SG, Carello G, Lanzarone E, Ocak Z, Indag SY. Management of Blood Donation System: Literature Review and Research Perspectives. Health Care Syst Eng Sci Pract. 2022;169:121–132. DOI: 10.1007/978-3-319-35132-2-12.

Belien J, Force H. Supply Chain Management of Blood Products: A Literature Review. Eur J Oper Res. 2021;217(1):1–16.

Shamshirian A, Mohseni AR, Pourfathollah AA, Mehdipour S, Hosseini S, Ghorbanpour A, Azizi S. A Review of Blood Usage and Wastage in a Tertiary Heart Center. Acta Clin Belg. 2020;75(2):96-103.

Samani MRG, Motlagh SMH, Ghannadpour SF. A Multilateral Perspective Towards Blood Network Design in an Uncertain Environment: Methodology and Implementation. Comput Ind Eng. 2019;130:450–471. DOI: 10.1016/j.cie.2019.02.049.

Shishavan SAS, Donyatalab Y, Farrokhizadeh E, Satoglu SI. A Fuzzy Optimization Model for Designing an Efficient Blood Supply Chain Network Under Uncertainty and Disruption. Ann Oper Res. 2021;331(1):12-13. DOI:10.1007/s10479-021-04123-y.

Testik MC, Ozkaya BY, Aksu S, Ozcebe OI. Discovering Blood Donor Arrival Patterns Using Data Mining: A Method to Investigate Service Quality at Blood Centers. J Med Syst. 2012;36(2):579-94. DOI: 10.1007/s10916-010-9519-7.

Webster J, Watson TJ. Analyzing the Past to Prepare for the Future: Writing a Literature Review. Manag Inf Syst Q. 2021;26(2):13–23.

Williams EP, Harper RR, Gartner D. Modeling of the Collections Process in the Blood Supply Chain: A Literature Review. IISE Trans Healthc Syst Eng. 2020;10(3):200–211.

Xu Y, Wood AM, Sweeting MJ, Roberts DJ, Tom BDM. Optimal Individualized Decision Rules From a Multi-Arm Trial: A Comparison of Methods and an Application to Tailoring Inter-Donation Intervals Among Blood Donors in the UK. Stat Methods Med Res. 2020;29(11):3113–3134.

Yalcındag S, Gure SB, Carello G, Lanzarone E. A Stochastic Risk-Averse Framework for Blood Donation Appointment Scheduling Under Uncertain Donor Arrivals. Health Care Manag Sci. 2020;23(4):535–555.

Zahiri B, Pishvaee MS. Blood Supply Chain Network Design Considering Blood Group Compatibility Under Uncertainty. Int J Prod Res. 2016;55(7):2021–2033.

Zahiri B, Torabi SA, Mousazadeh M, Mansouri SA. Blood Collection Management: Methodology and Application. Appl Math Model. 2015;39(23-24):7680–7696.

Lancet H. Updates on Blood Transfusion Guidelines. Lancet Haematol. 2016;3(12). DOI: 10.1016/S2352-3026(16)30172-7.

Pfuntner A, Wier LM, Stocks C. Most Frequent Procedures Performed in U.S. Hospitals, 2011: Statistical Brief #165. Healthcare Cost and Utilization Project (HCUP) Statistical Briefs. Rockville (MD): Agency for Healthcare Research and Quality (US); 2023. Available from: https://pubmed.ncbi.nlm.nih.gov/24354027/.

Raval JS, Griggs JR, Fleg A. Blood Product Transfusion in Adults: Indications, Adverse Reactions, and Modifications. Am Fam Physician. 2020;102(1):30-38.

Carson JL, Triulzi DJ, Ness PM. Indications for and Adverse Effects of Red-Cell Transfusion. N Engl J Med. 2017;377(13):1261-1272.

Hartmann J, Klein HG. Supply and Demand for Plasma-Derived Medicinal Products - A Critical Reassessment Amid the COVID-19 Pandemic. Transfus. 2020;60(11):2748-2752.

Bihl F, Castelli D, Marincola F, Dodd RY, Brander C. Transfusion-Transmitted Infections. J Transl Med. 2007;5:25. DOI: 10.1186/1479-5876-5-25.

Galel SA, Williamson PC, Busch MP. First Zika-Positive Donations in the Continental United States. Transfusion. 2017;57(3):762-769.

Saá P, Proctor M, Foster G. Investigational Testing for Zika Virus Among U.S. Blood Donors. N Engl J Med. 2018;378(19):1778-1788.

Moog FP, Karenberg A. Between Horror and Hope: Gladiator's Blood as a Cure for Epileptics in Ancient Medicine. J Hist Neurosci. 2003;12(2):137-43.

Cagliano AC, Grimaldi S, Rafele C. A Structured Approach to Analyse Logistics Risks in the Blood Transfusion Process. J Healthc Risk Manag. 2021;41(2):18-30.

The Strange, Grisly History of the First Blood Transfusion. Encyclopedia Britannica. 2021. Available from: https://www.britannica.com/story/the-strange-grisly-history-of-the-first-blood-transfusion.

Giangrande PL. The History of Blood Transfusion. Br J Haematol. 2000;110(4):758-767.

Saba N, Muhammad I, Waheed U, Latif Z, Ullah W, Muhammad N, Ali S. Seroepidemiology and Risk Factors Analysis of Syphilis: A Cross-Sectional Study From Peshawar, Pakistan. J Soc Obstet Gynaecol Pak. 2022;12(1):68-72.

Sultan S, Jaffri SA, Irfan SM, Usman SM, Nadeem S, Waheed U, Zaheer HA. An Insight Into Donor Blood Unit’s Wastage in a Hospital-Based Blood Bank From Pakistan. Int J Med Res Health Sci. 2021;10(5):91-5.

Arora I, Singh S, Singh S. Donor Blood Wastage: A Study From Blood Bank Chamba (HP). Int J Community Med Public Health. 2018;5(7):3016-9.

Downloads

Published

2024-08-15

How to Cite

Khalid, M., Khalid, M. N., Sadiq, F., Aslam, M., Begum, S., Qadri, U. K., Hashmi, M.-K. Q., Chaudhary, S. K., Zadran, R., & Ali, U. (2024). Optimizing Blood Management: A Comprehensive Study on Blood Transfusion Practices and Wastage Reduction Strategies at Tertiary Care Hospital: Optimization of Blood Transfusion Practices. Journal of Health and Rehabilitation Research, 4(3). https://doi.org/10.61919/jhrr.v4i3.1142

Most read articles by the same author(s)