Pattern of Daiabetic Retinopathy and its Effects on Health Related Quality of Life in In-Patients at Endocrinology Unit, Hayatabad Medical Complex Peshawar

Authors

  • Sara Saleem Public Health Department, Rehman College of Allied Health Sciences Peshawar Pakistan.
  • Muhammad Imshad Khan Rehman College of Allied Health Sciences Peshawar Pakistan.
  • Bilal Ahmad Rehman College of Allied Health Sciences Peshawar Pakistan.
  • Muhammad Numan Rehman College of Allied Health Sciences Peshawar Pakistan.
  • Arif Ullah Rehman College of Allied Health Sciences Peshawar Pakistan.
  • Noreen Fayaz Rehman College of Allied Health Sciences Peshawar Pakistan.
  • Uzma NCS University System Peshawar Pakistan.

DOI:

https://doi.org/10.61919/jhrr.v4i3.1171

Keywords:

Diabetes Mellitus, Diabetic Retinopathy, Vision related quality of life, Health related quality of life

Abstract

Introduction: Diabetes mellitus (DM) is a metabolic disorder, it affects the whole body, but it has serious effects on nerves, kidneys, heart and eyes. Diabetes mellitus causes retinopathy, which is one of the most significant consequences; high level of blood sugar damages the small blood vessels in the retina which is called microangiopathy. Diabetic retinopathy is one of the most common causes of acquired visual loss in working age group of adults and it has severe impact on the health related1quality of life (HRQoL).

Materials and Methods: This cross-sectional study was done at endocrinology unit of Hayatabad medical complex in six months’ period. The total sample size was 318. Data was collected from endocrinology unit with a validated questionnaire through nonprobability convenience sampling.DM diagnosed patients were selected and those who were not willing to participate and were physically not able to interact, were excluded from the study.

Results: There were 141(44.3%) male and 177(55.7%) female participants among the total 318 participants in the study.  Among these 56(17.6%) participants having mild diabetic retinopathy,81(25.5%) participants having moderate diabetic retinopathy,120(37.7%) participants having severe diabetic retinopathy while 61(19.2%) of the participants were not having clinically significant diabetic retinopathy. There was significant association of diabetic retinopathy with health-related quality of life (p value 0.04). There was a weak positive correlation between vision related quality of life (VRQOL) and the health related quality of life (HRQOL) relationship was positive (r (316(=0.124,p=0.027), it was statistically significant. The results showed that gender, socioeconomic condition, visual acuity, laser status for ocular problems, vitrectomy, and cataract has significant association with diabetic retinopathy

Conclusion: We conclude that diabetic retinopathy is quite prevalent in diabetic patients and is affecting the HRQOL. VRQOL is one of the associated factors resulting in poor HRQOL in these patients. Preventing measures including health education of the diabetic patients need to be ensured for regular ocular examination, to limit the complications of diabetes including poor HRQOL.

Downloads

Download data is not yet available.

Author Biographies

Sara Saleem, Public Health Department, Rehman College of Allied Health Sciences Peshawar Pakistan.

Lecturer, Department of Vision sciences, Rehman College of Allied Health Sciences, Peshawar, Pakistan.

Muhammad Imshad Khan, Rehman College of Allied Health Sciences Peshawar Pakistan.

Assistant Professor, Department of Vision sciences, Rehman College of Allied Health Sciences, Peshawar, Pakistan.

Bilal Ahmad, Rehman College of Allied Health Sciences Peshawar Pakistan.

Lecturer, Department of Public Health, Rehman College of Allied Health Sciences, Peshawar, Pakistan.

Muhammad Numan, Rehman College of Allied Health Sciences Peshawar Pakistan.

Lecturer, Department of Public Health, Rehman College of Allied Health Sciences, Peshawar, Pakistan.

Arif Ullah, Rehman College of Allied Health Sciences Peshawar Pakistan.

Lecturer, Department of Vision sciences, Rehman College of Allied Health Sciences, Peshawar, Pakistan.

Noreen Fayaz, Rehman College of Allied Health Sciences Peshawar Pakistan.

Lecturer, Department of Vision sciences, Rehman College of Allied Health Sciences, Peshawar, Pakistan.

Uzma, NCS University System Peshawar Pakistan.

Lecturer, Department of Dental Technology, NCS University System, Peshawar, Pakistan.

References

Association AD. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes care. 2003;26(suppl 1):s5-s20.

Ramm L, Herber R, Spoerl E, Pillunat LE, Terai N. Intraocular pressure measurements in diabetes mellitus. European journal of ophthalmology. 2020;30(6):1432-9.

Yau JW, Rogers SL, Kawasaki R, Lamoureux EL, Kowalski JW, Bek T, et al. Global prevalence and major risk factors of diabetic retinopathy. Diabetes care. 2012;35(3):556-64.

Cheung N, Mitchell P, Wong T. Diabetic retinopathy. Lancet [Internet]. 2010; 376 (9735): 124–36.

Villegas-Ruiz V, Hendlmeier F, Buentello-Volante B, Rodríguez-Loaiza JL, Miranda-Duarte A, Zenteno JC. Genome-wide mRNA analysis reveals a TUBD1 isoform profile as a potential biomarker for diabetic retinopathy development. Experimental eye research. 2017;155:99-106.

Amanda I, Zakaria H, editors. Development of diabetic retinopathy early detection and its implementation in Android application. AIP Conference Proceedings; 2019: AIP Publishing LLC.

Mumtaz SN, Fahim MF, Arslan M, Shaikh SA, Kazi U, Memon MS. Prevalence of diabetic retinopathy in Pakistan; A systematic review. Pakistan journal of medical sciences. 2018;34(2):493.

Soleimani Kamran J, Jafroudi S, KazemNejad Leili E, Sedighi Chafjiri A, Paryad E. Quality of life in patients with diabetic retinopathy. Journal of Holistic Nursing And Midwifery. 2017;27(1):69-77.

Lemeshow S, Hosmer DW, Klar J, Lwanga SK, Organization WH. Adequacy of sample size in health studies: Chichester: Wiley; 1990.

Social P. Living standards measurement survey (PSLM). Statistics Division, Government of Pakistan. 2004;5.

Malik S, Chaudhry IS, Javed HI. Globalization and Employment: Evidence from Pakistan. Pakistan Journal of Social Sciences (PJSS). 2011;31(2).

Tanzil S, Jamali T. Obesity, an emerging epidemic in Pakistan-a review of evidence. J Ayub Med Coll Abbottabad. 2016;28(3):597.

. !!! INVALID CITATION !!! (80-82).

Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD, et al. Retinopathy in diabetes. Diabetes care. 2004;27(suppl 1):s84-s7.

Gleicher N, Barad DH. Gender as risk factor for autoimmune diseases. Journal of autoimmunity. 2007;28(1):1-6.

. !!! INVALID CITATION !!! (100, 101).

Dandona L, Dandona R, Naduvilath TJ, McCarty CA, Rao GN. Population based assessment of diabetic retinopathy in an urban population in southern India. British Journal of Ophthalmology. 1999;83(8):937-40.

Ramachandran A, Snehalatha C, Vijay V, King H. Impact of poverty on the prevalence of diabetes and its complications in urban southern India. Diabetic Medicine. 2002;19(2):130-5.

Park YG, Roh Y-J. New Diagnostic and Therapeutic Approaches for Preventing the Progression of Diabetic Retinopathy. Journal of Diabetes Research. 2016;2016:1753584.

Yoshida S, Kubo Y, Kobayashi Y, Zhou Y, Nakama T, Yamaguchi M, et al. Increased vitreous concentrations of MCP-1 and IL-6 after vitrectomy in patients with proliferative diabetic retinopathy: possible association with postoperative macular oedema. British Journal of Ophthalmology. 2015;99(7):960-6.

Donaghue KC, Fairchild JM, Craig ME, Chan AK, Hing S, Cutler LR, et al. Do all prepubertal years of diabetes duration contribute equally to diabetes complications? Diabetes care. 2003;26(4):1224-9.

Klein R, Knudtson MD, Lee KE, Gangnon R, Klein BE. The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXII: the twenty-five-year progression of retinopathy in persons with type 1 diabetes. Ophthalmology. 2008;115(11):1859-68.

Klein R, Knudtson MD, Lee KE, Gangnon R, Klein BE. The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXIII: the twenty-five-year incidence of macular edema in persons with type 1 diabetes. Ophthalmology. 2009;116(3):497-503.

Klein BE, Klein R, Moss SE. Prevalence of cataracts in a population-based study of persons with diabetes mellitus. Ophthalmology. 1985;92(9):1191-6.

Küchle M, Naumann G. Studies of the blood-aqueous barrier in diabetes mellitus. American journal of ophthalmology. 1995;119(1):111-2.

Flammer J, Orgül S, Costa VP, Orzalesi N, Krieglstein GK, Serra LM, et al. The impact of ocular blood flow in glaucoma. Progress in retinal and eye research. 2002;21(4):359-93.

Nakamura M, Kanamori A, Negi A. Diabetes mellitus as a risk factor for glaucomatous optic neuropathy. Ophthalmologica. 2005;219(1):1-10.

Tielsch JM, Katz J, Quigley HA, Javitt JC, Sommer A. Diabetes, intraocular pressure, and primary open-angle glaucoma in the Baltimore Eye Survey. Ophthalmology. 1995;102(1):48-53.

Vijaya L, George R, Baskaran M, Arvind H, Raju P, Ramesh SV, et al. Prevalence of primary open-angle glaucoma in an urban south Indian population and comparison with a rural population: the Chennai Glaucoma Study. Ophthalmology. 2008;115(4):648-54. e1.

Pasquale LR, Kang JH, Manson JE, Willett WC, Rosner BA, Hankinson SE. Prospective study of type 2 diabetes mellitus and risk of primary open-angle glaucoma in women. Ophthalmology. 2006;113(7):1081-6.

Gabrielian A, Hariprasad S, Jager R, Green J, Mieler W. The utility of visual function questionnaire in the assessment of the impact of diabetic retinopathy on vision-related quality of life. Eye. 2010;24(1):29-35.

Meade T, Dowswell E. Health-related quality of life in a sample of Australian adolescents: gender and age comparison. Quality of Life Research. 2015;24(12):2933-8.

Weeks WB, Kazis LE, Shen Y, Cong Z, Ren XS, Miller D, et al. Differences in health-related quality of life in rural and urban veterans. American Journal of Public Health. 2004;94(10):1762-7.

Alonso J, Ferrer M, Gandek B, Ware JE, Aaronson NK, Mosconi P, et al. Health-related quality of life associated with chronic conditions in eight countries: results from the International Quality of Life Assessment (IQOLA) Project. Quality of life research. 2004;13(2):283-98.

Matza LS, Rousculp MD, Malley K, Boye KS, Oglesby A. The longitudinal link between visual acuity and health-related quality of life in patients with diabetic retinopathy. Health and quality of life outcomes. 2008;6(1):1-10.

Hyman LG, Komaroff E, Heijl A, Bengtsson B, Leske MC, Group EMGT. Treatment and vision-related quality of life in the early manifest glaucoma trial. Ophthalmology. 2005;112(9):1505-13.

Vashist P, Gupta N, Tandon R, Gupta SK, Dwivedi S, Mani K. Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study. British Journal of Ophthalmology. 2016;100(5):588-93.

Wu S-Y, Hennis A, Nemesure B, Leske MC. Impact of glaucoma, lens opacities, and cataract surgery on visual functioning and related quality of life: the Barbados Eye Studies. Investigative ophthalmology & visual science. 2008;49(4):1333-8.

Ahola AJ, Saraheimo M, Forsblom C, Hietala K, Sintonen H, Groop P-H, Group FS. Health-related quality of life in patients with type 1diabetes—association with diabetic complications (the FinnDiane Study). Nephrology Dialysis Transplantation. 2010;25(6):1903-8.

Swamy BN, Chia EM, Wang JJ, Rochtchina E, Mitchell P. Correlation between vision‐and health‐related quality of life scores. Acta ophthalmologica. 2009;87(3):335-9.

Downloads

Published

2024-07-31

How to Cite

Saleem, S., Khan, M. I., Ahmad, B., Numan, M., Ullah, A., Fayaz, N., & Uzma. (2024). Pattern of Daiabetic Retinopathy and its Effects on Health Related Quality of Life in In-Patients at Endocrinology Unit, Hayatabad Medical Complex Peshawar. Journal of Health and Rehabilitation Research, 4(3), 1–9. https://doi.org/10.61919/jhrr.v4i3.1171