The Effect of Laser-Assisted in Situ Keratomileusis on Endothelial Cell Count

LASIK and Endothelial Cell Count

Authors

  • Khola Khan Department of Ophthalmology, Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, Pakistan
  • Abdul Rauf Department of Ophthalmology, Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, Pakistan
  • Ijlal Taimoor Department of Ophthalmology, Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, Pakistan
  • Teyyeb Azeem Janjua Department of Ophthalmology, Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, Pakistan
  • Umar Ijaz Department of Ophthalmology, Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, Pakistan
  • Farheen Department of Ophthalmology, Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, Pakistan
  • Muhammad Farrukh Habib Department of Management Sciences, Shifa Tameer E Millat University, Islamabad, Pakistan.

DOI:

https://doi.org/10.61919/jhrr.v4i3.1398

Keywords:

LASIK, endothelial cell count, myopia, refractive surgery, corneal thickness, visual acuity, corneal health, specular microscopy, ophthalmology, patient outcomes.

Abstract

Background: LASIK is a popular refractive surgery for correcting myopia, but its impact on endothelial cell count (ECC) remains uncertain, with potential implications for corneal health.
Objective: To determine the effect of LASIK on ECC in myopic patients.
Methods: A cross-sectional study was conducted at Military Hospital, Rawalpindi, from January to July 2023. A total of 178 myopic patients (38.76% males, 61.24% females; mean age 25.21 ± 8.19 years) underwent LASIK. Baseline and post-procedural ECC were measured using specular microscopy at one week, one month, and three months post-LASIK. Central corneal thickness (CCT) and best corrected visual acuity (BCVA) were also assessed. Data analysis was performed using SPSS version 25, with paired t-tests for comparisons and significance set at p ≤ 0.05.
Results: Mean ECC decreased from 2897.49 ± 93.52 cells/mm² at baseline to 2892.36 ± 94.21 cells/mm² at one week, 2846.65 ± 93.80 cells/mm² at one month, and 2811.10 ± 90.66 cells/mm² at three months post-LASIK (p < 0.001). Mean CCT also significantly decreased at all time points (p < 0.001).
Conclusion: LASIK significantly reduces ECC, highlighting the need for careful postoperative monitoring of corneal health.

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References

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Published

2024-09-17

How to Cite

Khola Khan, Abdul Rauf, Ijlal Taimoor, Teyyeb Azeem Janjua, Umar Ijaz, Farheen, & Muhammad Farrukh Habib. (2024). The Effect of Laser-Assisted in Situ Keratomileusis on Endothelial Cell Count: LASIK and Endothelial Cell Count. Journal of Health and Rehabilitation Research, 4(3), 1–4. https://doi.org/10.61919/jhrr.v4i3.1398

Issue

Vol. 4 No. 3 (2024): Volume 4, Issue 3 - July to September 2024

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Copyright (c) 2024 Khola Khan, Abdul Rauf, Ijlal Taimoor, Teyyeb Azeem Janjua, Umar Ijaz, Farheen, Muhammad Farrukh Habib

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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