A Double-Blind Split Mouth Study Comparing the Effects of 5% EMLA Cream and 20% Benzocaine on Pre-Injection Analgesia

EMLA vs. Benzocaine for Pre-Injection Analgesia

Authors

  • Shaharyar Hamid Shaikh Dow University of health sciences Karachi, Pakistan
  • Anwar Ali Dow University of health sciences Karachi, Pakistan
  • Muhammad Ilyas Dow University of health sciences Karachi, Pakistan
  • Safia Khatoon Jinnah Sindh Medical University Karachi
  • Syeda Noureen Iqbal Dow University of health sciences Karachi, Pakistan
  • Daud Sultan Dow University of health sciences Karachi, Pakistan

DOI:

https://doi.org/10.61919/jhrr.v4i3.1415

Keywords:

EMLA Cream , Benzocaine Gel , Pre-Injection Analgesia , Dental Pain Management

Abstract

Background: Pain during local anesthetic injections is a common concern in dental procedures, often managed by topical anesthetics. However, no topical anesthetic has entirely eliminated this pain.
Objective: To compare the effectiveness of 5% EMLA cream and 20% benzocaine gel in reducing pre-injection pain.
Methods: A double-blind, split-mouth clinical trial was conducted with 70 participants, aged 18-35 years, undergoing bilateral dental extractions. 5% EMLA cream and 20% benzocaine gel were applied to separate sites before injection. Pain was assessed using a Visual Analog Scale (VAS) at 3, 6, and 9 minutes post-administration. Data were analyzed using an independent sample t-test with significance set at p ≤ 0.05.
Results: The EMLA group showed significantly lower VAS scores compared to the benzocaine group at 3 minutes (3.00 ± 2.04 vs. 4.00 ± 1.00, p = 0.035), 6 minutes (3.00 ± 2.04 vs. 4.23 ± 1.38, p = 0.005), and 9 minutes (3.00 ± 2.04 vs. 4.00 ± 1.53, p = 0.004).
Conclusion: EMLA cream was more effective than benzocaine gel in reducing pre-injection pain. Clinicians should consider EMLA as a preferred option for enhanced patient comfort.

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Published

2024-08-17

How to Cite

Shaharyar Hamid Shaikh, Anwar Ali, Muhammad Ilyas, Safia Khatoon, Syeda Noureen Iqbal, & Daud Sultan. (2024). A Double-Blind Split Mouth Study Comparing the Effects of 5% EMLA Cream and 20% Benzocaine on Pre-Injection Analgesia: EMLA vs. Benzocaine for Pre-Injection Analgesia. Journal of Health and Rehabilitation Research, 4(3), 1–4. https://doi.org/10.61919/jhrr.v4i3.1415

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