Role of Plants in the Treatment of Diseases Caused by Microorganisms Based on Natural Products Role of Plants in Treating Microbial Diseases
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Abstract
Background: Antimicrobial resistance (AMR) poses a critical global health challenge, leading to prolonged disease duration, increased mortality, and economic burden. The use of plant-based natural products offers a potential alternative to traditional antibiotics due to their bioactive compounds.
Objective: To evaluate the efficacy of plant-derived compounds in the treatment of diseases caused by microbial pathogens and their potential role in overcoming AMR.
Methods: A cross-sectional study design was employed involving 200 microbiology patients. Data were collected through structured surveys, interviews, and laboratory testing of various plant extracts (garlic, neem, oregano). The antibacterial activity of these extracts was assessed using the agar diffusion method and Minimum Inhibitory Concentration (MIC) assays. Statistical analyses, including independent t-tests, correlation, and regression, were performed using SPSS.
Results: Plant extracts demonstrated strong antimicrobial activity with garlic showing inhibition zones of 15mm, neem 18mm, and oregano 20mm. Regression analysis confirmed the significant role of plant compounds in inhibiting microbial growth (β = 0.250, p = 0.001, R² = 0.065).
Conclusion: Plant-based compounds are promising candidates for treating microbial infections and managing AMR. Further research and clinical validation are recommended.
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