A Review on the Effects of Daily Use Chemicals on Human Health

Authors

  • Muhammad Haseeb Hassan Department of Chemistry, University of Agriculture Faisalabad, Punjab, Pakistan
  • Fatima Nadeem Department of Chemistry, Superior University Lahore, Punjab, Pakistan
  • Rumasa Asif Department of Biochemistry, University of Agriculture Faisalabad, Punjab, Pakistan
  • Areeb Ahmed Department of Biotechnology, Gulab Devi Education Complex, Punjab, Pakistan
  • Abdul Muneb Ahmad Department of Chemistry, Superior University Lahore, Punjab, Pakistan
  • Ghulam Junaid Department of Biochemistry, University of Agriculture Faisalabad, Punjab, Pakistan
  • Tayyaba Yousif Department of Microbiology, Superior University Lahore, Punjab, Pakistan
  • Muhammad Tahir Zaman Department of chemistry, School of Science, University of Management and Technology, Lahore, Pakistan

DOI:

https://doi.org/10.61919/jhrr.v4i3.1803

Keywords:

Daily-use chemicals; Human health risks; Endocrine disruptors; Chemical regulation; Eco-friendly alternatives

Abstract

Everyday chemicals found in personal care products, cleaning products, plastics, and household items are increasingly recognized as contributors to a wide range of adverse health effects. Those chemicals include phthalates, parabens, bisphenol A (BPA), triclosan, synthetic fragrances, and flame retardants, many of which have been linked to endocrine disruption, neurodevelopmental disorders, reproductive toxicity, metabolic disorders, and some cancers. This review combines the results of contemporary toxicological and epidemiological research to provide a comprehensive overview of human exposure pathways, mechanisms of toxic action, and associated health risks. Special attention is paid to sensitive groups such as infants, children, pregnant women, and people with pre-existing disease, who are likely to be more affected by chronic exposure to low doses of these contaminants. The article also discusses international control policies such as the U.S. Toxic Substances Control Act (TSCA), the Food and Drug Administration’s Consumer Products Regulations, and the European Union’s REACH regulations. While some progress has been made in banning or restricting certain toxic chemicals, enforcement is still spotty, and thousands of chemicals are still used without proper safety assessments. Furthermore, shortcomings in the science base of regulations such as the failure to assess aggregate exposures and chemical combinations create formidable obstacles to protecting public health. To address these challenges, the review discusses alternative options, from natural and environmentally friendly consumer products to the importance of public education in reducing exposure. Proposed policy recommendations include adopting the precautionary principle, accelerating international harmonization, increasing green chemistry research funding, and expanding biomonitoring programs. Finally, this review emphasizes the urgent need for integrated, science-based strategies in chemical safety that integrate regulatory reform, public education, and industrial innovation to reduce the health risks of everyday chemicals and ensure long-term environmental and human health sustainability.

Downloads

Download data is not yet available.

References

Bouchard MF, Chevrier J, Harley KG, Kogut K, Vedar M, Calderon N, et al. Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. Environ Health Perspect. 2011;119(8):1189–95. https://doi.org/10.1289/ehp.1003185

Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, Hauser R, Prins GS, Soto AM, et al. Endocrine-disrupting chemicals: An Endocrine Society scientific statement. Endocr Rev. 2009;30(4):293–342. https://doi.org/10.1210/er.2009-0002

Dixon HG, Borland R, Segan CJ, Stafford H. Public education campaigns and their impact on reducing exposure to harmful chemicals: A systematic review. Int J Environ Res Public Health. 2021;18(9):4570. https://doi.org/10.3390/ijerph18094570

Dodson RE, Nishioka M, Standley LJ, Perovich LJ, Brody JG, Rudel RA. Endocrine disruptors and asthma-associated chemicals in consumer products. Environ Health Perspect. 2012;120(7):935–43. https://doi.org/10.1289/ehp.1104052

Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, et al. EDC-2: The Endocrine Society's second scientific statement on endocrine-disrupting chemicals. Endocr Rev. 2015;36(6):E1–150. https://doi.org/10.1210/er.2015-1010

Harley KG, Kogut K, Madrigal DS, Cardenas M, Vera IA, Meza-Alfaro G, et al. Reducing phthalate, paraben, and phenol exposure from personal care products in adolescent girls: Findings from the HERMOSA intervention study. Environ Health Perspect. 2016;124(10):1600–7. https://doi.org/10.1289/EHP178

Janjua NR, Frederiksen H, Skakkebaek NE, Wulf HC, Andersson AM. Urinary excretion of phthalates and parabens after repeated whole-body topical application in humans. Int J Androl. 2008;31(2):118–30. https://doi.org/10.1111/j.1365-2605.2007.00841.x

Landrigan PJ, Fuller R. Environmental pollution: An under-recognized threat to children's health, especially in low- and middle-income countries. Environ Health Perspect. 2015;123(3):A68–70. https://doi.org/10.1289/ehp.1409515

Landrigan PJ, Raps H, Cropper M, Stegeman JJ. The need for a global chemical safety initiative. Lancet Planet Health. 2020;4(11):e521–3. https://doi.org/10.1016/S2542-5196(20)30227-6

Quinn MM, Henneberger PK, Braun B, Delclos GL, Fagan K, Huang V, et al. Cleaning and disinfecting environmental surfaces in health care: Toward an integrated framework for infection and occupational illness prevention. Am J Infect Control. 2015;43(5):424–34. https://doi.org/10.1016/j.ajic.2015.01.029

Rochester JR. Bisphenol A and human health: A review of the literature. Reprod Toxicol. 2013;42:132–55. https://doi.org/10.1016/j.reprotox.2013.08.008

Schecter A, Malik N, Haffner D, Smith S, Harris TR, Paepke O, et al. Bisphenol A (BPA) in U.S. food. Environ Sci Technol. 2010;44(24):9425–30. https://doi.org/10.1021/es102785d

Svanes Ø, Skorge TD, Johannessen A, Bertelsen RJ, Bråbäck L, Dharmage SC, et al. Cleaning at home and at work in relation to lung function decline and airway obstruction. Am J Respir Crit Care Med. 2018;197(9):1157–63. https://doi.org/10.1164/rccm.201706-1311OC

Swan SH, Main KM, Liu F, Stewart SL, Kruse RL, Calafat AM, et al. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect. 2005;113(8):1056–61. https://doi.org/10.1289/ehp.8100

Tickner JA, Jacobs MM, Edwards S. Evaluating chemical safety policies in the United States and the European Union: Different approaches, similar outcomes? Environ Sci Technol. 2019;53(2):703–11. https://doi.org/10.1021/acs.est.8b05207

Trasande L, Lampa E, Lind L, Bornehag CG. Chemical policy reforms for prevention of disease and healthcare savings: A call to action. Lancet Diabetes Endocrinol. 2020;8(8):580–2. https://doi.org/10.1016/S2213-8587(20)30118-3

Trasande L, Zoeller RT, Hass U, Kortenkamp A, Grandjean P, Myers JP, et al. Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: An updated analysis. Andrology. 2018;6(5):728–36. https://doi.org/10.1111/andr.12538

Zota AR, Phillips CA, Mitro SD. Recent fast food consumption and bisphenol A and phthalates exposures among the U.S. population in NHANES, 2003–2010. Environ Health Perspect. 2016;124(10):1521–8. https://doi.org/10.1289/ehp.1510803

Downloads

Published

2024-09-26

How to Cite

Haseeb Hassan, M., Fatima Nadeem, Rumasa Asif, Areeb Ahmed, Abdul Muneb Ahmad, Ghulam Junaid, Tayyaba Yousif, & Muhammad Tahir Zaman. (2024). A Review on the Effects of Daily Use Chemicals on Human Health. Journal of Health and Rehabilitation Research, 4(3), 1–8. https://doi.org/10.61919/jhrr.v4i3.1803