The Burden of Post-Stroke Depression and Anxiety Among Stroke Patients Admitted to Tertiary Care Teaching Hospitals of Khyber Pakhtunkhwa.
Main Article Content
Abstract
Background: Stroke, a leading cause of disability and mortality worldwide, is often accompanied by post-stroke depression (PSD) and anxiety, significantly impacting the quality of life of survivors. In Khyber Pakhtunkhwa, there is a notable prevalence of stroke-related complications, influenced by factors like obesity, hypertension, and diabetes mellitus.
Objective: This study aimed to determine the frequency of PSD and anxiety among stroke patients admitted to tertiary care hospitals in Khyber Pakhtunkhwa, with a focus on understanding the distribution of these conditions among different demographic groups.
Methods: A descriptive cross-sectional study was conducted over six months (March 2021 - August 2021). Participants included both genders, aged above 18, who were victims of acute post-stroke events, and capable of communication. The sample size of 109 was calculated using Raosoft software. Data collection employed the Hospital Anxiety and Depression Scale (HADS), and SPSS version 25 was used for data analysis. Descriptive statistics, histograms, pie charts, and tables were utilized for data representation.
Results: The study revealed that 63.3% of participants suffered from depression and 83.5% from anxiety. Of these, 46.8% scored in the 'abnormal' range for anxiety, and 42.2% for depression. Females constituted 54.13% of the participants, while 45.87% were males. Hemorrhagic stroke (51.85%) was more common than ischemic stroke (48.15%).
Conclusion: The high prevalence of PSD and anxiety among stroke patients in Khyber Pakhtunkhwa necessitates the incorporation of comprehensive mental health care in stroke rehabilitation programs. Tailored interventions addressing PSD and anxiety are crucial for improving patient outcomes.
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References
Cross JG, May BR, Mai PQ, Anderson E, Welsh C, Chandran S, et al. A systematic review and evaluation of post-stroke depression clinical practice guidelines. 2023;32(9):107292.
Venketasubramanian N, Yoon BW, Pandian J, Navarro JCJJos. Stroke epidemiology in south, east, and south-east asia: A review. 2017;19(3):286.
Ibrahimagic OC, Smajlovic D, Kunic S, Dostovic Z, Custovic A, Sehanovic A, et al. Post-stroke depression. 2019;31(1):31.
Frank D, Gruenbaum BF, Zlotnik A, Semyonov M, Frenkel A, Boyko MJIJoMS. Pathophysiology and current drug treatments for post-stroke depression: A review. 2022;23(23):15114.
Sherin A, Ul-Haq Z, Fazid S, Shah BH, Khattak MI, Nabi FJPjoms. Prevalence of stroke in Pakistan: Findings from Khyber Pakhtunkhwa integrated population health survey (KP-IPHS) 2016-17. 2020;36(7):1435.
Kuriakose D, Xiao ZJIjoms. Pathophysiology and treatment of stroke: present status and future perspectives. 2020;21(20):7609.
Donkor ESJSr, treatment. Stroke in the century: a snapshot of the burden, epidemiology, and quality of life. 2018;2018.
Daviu N, Bruchas MR, Moghaddam B, Sandi C, Beyeler AJNos. Neurobiological links between stress and anxiety. 2019;11:100191.
Xie J, Geng X, Fan F, Fu X, He S, Li TJFiAN. The efficacy of therapies for post-stroke depression in aging: An umbrella review. 2022;14:993250.
Srivastava A, Taly AB, Gupta A, Murali TJAoIAoN. Post-stroke depression: prevalence and relationship with disability in chronic stroke survivors. 2010;13(2):123.
Guo J, Wang J, Sun W, Liu XJJon. The advances of post-stroke depression: 2021 update. 2022:1-14.
Robinson RG, Jorge REJAJoP. Post-stroke depression: a review. 2016;173(3):221-31.
Wijeratne T, Sales C, Wijeratne CJPR, Management B. A narrative review on the non-pharmacologic interventions in post-stroke depression. 2022:1689-706.
Staub F, Bogousslavsky J. Post-stroke depression or fatigue? European neurology. 2019;45(1):3-5.
Kwong JS, Yu C-M. New oral anticoagulants in acute coronary syndromes: what does a meta-analysis tell us? JAMA internal medicine. 2016;173(9):835-6.
Khalid W, Rozi S, Ali TS, Azam I, Mullen MT, Illyas S, et al. Quality of life after stroke in Pakistan. BMC neurology. 2016;16(1):1-12.
Farrag A-KF, Farwiz HM, Khedr EH, Mahfouz RM, Omran SM. Prevalence of Alzheimer’s disease and other dementing disorders: Assiut-Upper Egypt study. Dementia and geriatric cognitive disorders. 2017;9(6):323-8.
Dieguez S, Staub F, Bruggimann L, Bogousslavsky J. Is poststroke depression a vascular depression? Journal of the neurological sciences. 2015;226(1-2):53-8.
Hackett ML, Pickles K. Part I: frequency of depression after stroke: an updated systematic review and meta-analysis of observational studies. International Journal of Stroke. 2015;9(8):1017-25.
Ritter W, Vaughan HG. Averaged evoked responses in vigilance and discrimination: a reassessment. Science. 2015;164(3877):326-8.