Correlation of Coronary Artery Disease in Patients with Peripheral Artery Disease: Cross-Sectional Study

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Ajab Khan
Muhammad Gibran Khan
Imran Khan Khalil
Shahzad Khan
Hussain shah
Haider Ali Khan


Background Peripheral Artery Disease (PAD) and Coronary Artery Disease (CAD) represent two facets of atherosclerotic cardiovascular disease, significantly impacting global health. Despite their high morbidity and mortality rates, the epidemiological and clinical nexus between PAD and CAD remains underexplored. Understanding the interrelation of these conditions is paramount for optimizing diagnostic and therapeutic strategies.

Objective This study aimed to delineate the incidence and clinical correlation of CAD in patients diagnosed with PAD, thereby providing insights into the epidemiological characteristics and enhancing the clinical management of these conditions.

Methods A cross-sectional analysis was conducted at Afridi Medical Complex's departments of vascular surgery and cardiology from 2021 to 2023. One hundred PAD patients referred for peripheral angiography were enrolled. Demographic data, Ankle Brachial Index (ABI) readings, ejection fraction percentages, and the presence of multivessel disease were evaluated. Statistical analyses were performed using SPSS version 25, focusing on mean, median, range, and significance levels to elucidate the prevalence of CAD among PAD patients.

Results The study revealed a median age of 58 years among participants, with a significant male predominance (84%). ABI analysis showed that 74% and 108% of patients had mild and moderate PAD severity, respectively. The incidence of CAD in the PAD population was 56%, with angiographic assessments indicating single, double, and triple vessel disease in 23.21%, 39.29%, and 37.5% of patients, respectively. Notably, diabetes and dyslipidemia were prominent predictors of CAD presence in PAD patients.

Conclusion The high prevalence of CAD in PAD patients underscores the critical need for comprehensive cardiovascular risk assessment and suggests the potential benefit of routine coronary angiography in symptomatic PAD cases, particularly among those with diabetes and dyslipidemia. This study reinforces the intertwined nature of PAD and CAD, advocating for an integrated approach to the diagnosis and management of these atherosclerotic conditions.

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How to Cite
Khan, A., Khan , M. G., Khalil , I. K., Khan, S., shah , H., & Khan, H. A. (2024). Correlation of Coronary Artery Disease in Patients with Peripheral Artery Disease: Cross-Sectional Study. Journal of Health and Rehabilitation Research, 4(1), 1490–1497.
Author Biographies

Ajab Khan, Afridi Medical Complex and Teaching Hospital Pakistan.

Assistant Professor, Afridi Medical Complex and Teaching Hospital, Pakistan.

Muhammad Gibran Khan , Peshawar General Hospital Hayatabad Pakistan.

Assistant Professor, Peshawar General Hospital Hayatabad, Pakistan.

Imran Khan Khalil , MMC General Hospital Pakistan.

Consultant cardiac surgeon, MMC General Hospital, Pakistan.

Shahzad Khan, Peshawar General Hospital Hayatabad Pakistan.

Registrar, Peshawar General Hospital Hayatabad, Pakistan.

Hussain shah , Peshawar General Hospital Hayatabad Pakistan.

Registrar, Peshawar General Hospital Hayatabad, Pakistan.

Haider Ali Khan, Afridi Medical Complex Peshawar Pakistan.

Consultant Physiotherapist, Physiotherapy Dept, Afridi Medical Complex Peshawar, Pakistan.


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