Spontaneous Preterm Premature Rupture of Membranes and Related Consequences: A Case Series Analysis of Pregnant Women

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Published: Mar 31, 2024
DOI: https://doi.org/10.61919/jhrr.v4i1.697
Keywords:
Preterm Premature Rupture of Membranes (pPROM) Perinatal Morbidity Perinatal Mortality Obstetric Care Neonatal Outcomes Maternal Health SPSS Analysis Case Series

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Farheena Talha
People’s Medical College Hospital SBA Nawabshah Pakistan.
Parus Saleem
People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.
Riaz Mangi
People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.
Aqsa Kalhoro
People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.
Sikandar Arain
People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.
Abdul Razzaque Nohri
Liaquat University of Medical & Health Sciences LUMHS Jamshoro Pakistan.

Abstract

Background: Preterm premature rupture of membranes (pPROM) poses a significant challenge in obstetrics, associated with considerable perinatal morbidity and mortality. Despite advancements in healthcare, the management and outcomes of pPROM remain areas of concern, necessitating further investigation into effective strategies for prevention and treatment.


Objective: This study aims to investigate the maternal and neonatal outcomes associated with pPROM to develop targeted interventions that can mitigate the associated morbidity and mortality.


Methods: Conducted at GU-IV LUMHS, Jamshoro, over a six-month period from March to September 2018, this case series involved 116 pregnant women aged 20 to 30 years diagnosed with pPROM. Using non-probability consecutive sampling, participants were selected based on specific inclusion and exclusion criteria. Data were collected on demographic characteristics, clinical findings, and outcomes post-pPROM using a pre-designed proforma, following ethical standards aligned with the Declaration of Helsinki. The study employed SPSS version 25 for statistical analysis, calculating means, standard deviations, and employing chi-square tests for categorical variables, with a significance level set at p<0.05.


Results: The mean age of participants was 24.96 ± 2.63 years. Maternal complications included chorioamnionitis (11.21%), while neonatal outcomes revealed preterm births (42.24%), stillbirths (10.34%), and early neonatal deaths (12.93%). The comparison with previous studies highlighted a consistent age range vulnerability and underscored the critical outcomes of pPROM, such as high rates of preterm births and associated neonatal complications.


Conclusion: The study emphasizes the persistent challenges posed by pPROM in obstetric care, highlighting the need for enhanced diagnostic and management protocols. Improved understanding and interventions are crucial for reducing the adverse outcomes associated with pPROM, enhancing maternal and neonatal health.

Article Details

How to Cite
Talha, F., Saleem, P., Mangi, R., Kalhoro, A., Arain, S., & Nohri, A. R. (2024). Spontaneous Preterm Premature Rupture of Membranes and Related Consequences: A Case Series Analysis of Pregnant Women. Journal of Health and Rehabilitation Research, 4(1), 1723–1727. https://doi.org/10.61919/jhrr.v4i1.697
Issue
Vol. 4 No. 1 (2024): Volume 4, Issue 1 - January to March 2024
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Farheena Talha, People’s Medical College Hospital SBA Nawabshah Pakistan.

Women Medical Officer, People’s Medical College Hospital SBA Nawabshah Pakistan.

Parus Saleem, People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.

Assistant Professor, Department of Community Medicine, People's University of Medical and Health Sciences for Women PUMHSW SBA, Nawabshah, Pakistan.

Riaz Mangi, People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.

Assistant Professor, Department of Community Medicine, People's University of Medical and Health Sciences for Women PUMHSW SBA, Nawabshah, Pakistan.

Aqsa Kalhoro, People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.

Lecturer, Institute of Public Health, People's University of Medical and Health Sciences for Women PUMHSW SBA, Nawabshah, Pakistan.

Sikandar Arain, People's University of Medical and Health Sciences for Women PUMHSW SBA Nawabshah Pakistan.

Statistician, People's University of Medical and Health Sciences for Women PUMHSW SBA, Nawabshah, Pakistan.

Abdul Razzaque Nohri, Liaquat University of Medical & Health Sciences LUMHS Jamshoro Pakistan.

Senior Pharmacist, Health Department Government of Sindh, Pakistan. MSPH Candidate, Liaquat University of Medical and Health Sciences LUMHS Jamshoro, Pakistan.

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