Pineal Gland Epidermoid cyst, a rare Tumor

Main Article Content

Muhammad Ali Hassan
Muhammad Nadeem
Shahid Ahmed Shah
Hamaida Akbar
Syed Vaqar


Background: Intracranial epidermoid cysts, forming 1% of adult and 3-8% of pediatric brain tumors, are among the rarest of intracranial neoplasms. Originating from ectodermal remnants retained during embryonic development, pineal epidermoid cysts are rare benign tumors that often manifest as obstructive hydrocephalus due to midbrain tectum compression.

Objective: To report on the clinical presentation, diagnostic process, and surgical management of a pineal epidermoid cyst in a young adult, emphasizing the role of ventriculoperitoneal shunting and the outcomes of surgical intervention.

Methods: A case study of a 20-year-old male presenting with a 4-month history of occipital headaches and vertigo, without seizures, neurological deficits, or visual disturbances. Diagnostic evaluation included brain imaging that revealed hydrocephalus secondary to a pineal space-occupying lesion. A ventriculoperitoneal shunt was placed for obstructive hydrocephalus treatment prior to the surgical excision of the pineal lesion.

Results: The patient underwent a ventriculoperitoneal shunting procedure, followed by a suboccipital transtentorial craniotomy 2 months later, leading to the complete resection of the pineal space-occupying lesion. The histopathological analysis confirmed the diagnosis of a pineal epidermoid cyst. Post-surgical follow-up indicated significant symptomatic improvement with no recurrence observed.

Conclusion: Pineal epidermoid cysts, while rare, can significantly impact patient well-being through the development of obstructive hydrocephalus. Early intervention with ventriculoperitoneal shunting followed by surgical resection can lead to favorable outcomes. Long-term monitoring is essential to ensure there is no recurrence.

Article Details

How to Cite
Hassan , M. A., Nadeem , M., Shah, S. A., Akbar, H., & Vaqar , S. (2024). Pineal Gland Epidermoid cyst, a rare Tumor. Journal of Health and Rehabilitation Research, 4(2), 49–52.
Author Biographies

Muhammad Ali Hassan , Shifa International Hospital Islamabad Pakistan.

Shifa International Hospital Islamabad Pakistan.


Muhammad Nadeem , Shifa International Hospital Islamabad Pakistan.

Department of Neurosurgery, Shifa International Hospital Islamabad Pakistan.

Shahid Ahmed Shah, Shifa International Hospital Islamabad Pakistan.

Department of Neurosurgery, Shifa International Hospital Islamabad Pakistan.

Hamaida Akbar, Ghurki Trust Hospital Lahore Pakistan.

Ghurki Trust Hospital Lahore, Pakistan.


Syed Vaqar , Shifa International Hospital Islamabad Pakistan.

Department of Neurosurgery, Shifa International Hospital Islamabad, Pakistan.



Senapati SB, Mishra SS, Patnaik A, Patra SK. Pineal epidermoid. Surg Neurol Int. 2012;3:125.

Dr Pulkit Rangarh DSY, Prof Neera Kohli,Prof Anit Parihar. MR imaging findings in pineal epidermoid cyst with review of lierature. EURORAD2017.

Hassani FD, Bouchaouch A, El Fatemi N, Gana R, El Abbadi N, Maaqili MR. Pineal epidermoid cyst: case report and review of the literature. Pan African Medical Journal. 2014;18(1).

Jamali M, Ahrari I, Saffarrian A, Eghbal K, Rakhsha A, Ghahramani S. An Unusual Dermoid Cyst of the Pineal Region: Case report in a Child. Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery. 2021;40(01):097-100.

Handattu K, Yellanthoor RB, Kini S. Unilateral lateral rectus palsy: an unusual presentation of pineal epidermoid cyst. Pan African Medical Journal. 2020;36(1).

Zaccagna F, Brown F, Allinson K, Devadass A, Kapadia A, Massoud T, et al. In and around the pineal gland: a neuroimaging review. Clinical Radiology. 2022;77(2):e107-e19.

Szathmari A, Vasiljevic A, Di Rocco F, Beuriat P-A, Mottolese C. Pineal cysts in children: a paediatric series treated over the last twenty years in Lyon. Child's Nervous System. 2023;39(12):3467-74.

Chougule M, Chougule M. Benign Cysts of CNS. Neuropathology of Brain Tumors with Radiologic Correlates. 2020:345-55.

Guo F. Dermoid and Epidermoid Cyst. Incidental Findings of the Nervous System: Springer; 2023. p. 55-70.

Lombardi G, Poliani PL, Manara R, Berhouma M, Minniti G, Tabouret E, et al. Diagnosis and treatment of pineal region tumors in adults: a EURACAN overview. Cancers. 2022;14(15):3646.

Bosnjak J, Budisic M, Azman D, Strineka M, Crnjakovic M, Demarin V. Pineal gland cysts–an overview. Acta Clin Croat. 2009;48(3):355-8.

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