Diagnostic Accuracy of Color and Spectral Doppler in Identifying Endometrial Cancer in Post-Menopausal Menometrorrhagial Patients with Histopathology as Gold Standard

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Published: May 24, 2024
DOI: https://doi.org/10.61919/jhrr.v4i2.930
Keywords:
Doppler Ultrasonography, Endometrial Cancer, Non-invasive Diagnosis, Postmenopausal Hemorrhage, Sensitivity, Specificity, Ultrasonography

Main Article Content

Muhammad Ahmad Raza
University of Lahore-Lahore Pakistan.
Sana Habib
Al-Hadi Medical Complex Bhakkar Pakistan.
Bushra Akmal Khan
Hayatabad Medical Complex Peshawar Pakistan.
Laamia Altuf
Superior University Lahore Pakistan.
Saima Arshad
National Conservation Strategy Institute of Sciences Islamabad Pakistan.
Iqra Mussarat
University of Lahore-Lahore Pakistan.
Sidra Ghazanfar
University of Lahore-Lahore Pakistan.

Abstract

Background: Endometrial cancer is the most common gynecological malignancy in postmenopausal women, often presenting with postmenopausal hemorrhage. Traditional diagnostic methods are invasive, prompting the need for less intrusive, accurate alternatives.


Objective: To evaluate the efficacy of Doppler ultrasonography in diagnosing endometrial cancer in postmenopausal women presenting with hemorrhage, using histopathology as the gold standard.


Methods: This cross-sectional study was conducted at the University of Lahore Teaching Hospital from September 2023 to March 2024, involving 140 postmenopausal women. Participants underwent transvaginal and transabdominal ultrasonography, including color and spectral Doppler assessments. Doppler findings were compared with histopathological outcomes following biopsy.


Results: Doppler ultrasonography demonstrated a sensitivity of 78.63%, specificity of 65.22%, positive predictive value of 92.00%, negative predictive value of 37.50%, and overall diagnostic accuracy of 76.43%. Stratification analysis further indicated that the accuracy exceeded 90% in detecting endometrial cancer.


Conclusion: Doppler ultrasonography is a valuable non-invasive diagnostic tool for detecting endometrial cancer in postmenopausal women with hemorrhage. It offers high sensitivity and specificity, reducing the necessity for invasive diagnostic procedures.

Article Details

How to Cite
Raza, M. A., Habib, S., Khan, B. A., Altuf, L., Arshad, S., Mussarat, I., & Ghazanfar, S. (2024). Diagnostic Accuracy of Color and Spectral Doppler in Identifying Endometrial Cancer in Post-Menopausal Menometrorrhagial Patients with Histopathology as Gold Standard. Journal of Health and Rehabilitation Research, 4(2), 910–915. https://doi.org/10.61919/jhrr.v4i2.930
Issue
Vol. 4 No. 2 (2024): Volume 4, Issue 2 - April to June 2024
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Muhammad Ahmad Raza, University of Lahore-Lahore Pakistan.

MSDU - University Institute of Radiological Science & MIT, University of Lahore-Lahore, Pakistan.

Sana Habib, Al-Hadi Medical Complex Bhakkar Pakistan.

Sonographer - Al-Hadi Medical Complex Bhakkar, Pakistan.

Bushra Akmal Khan, Hayatabad Medical Complex Peshawar Pakistan.

Department - Hayatabad Medical Complex Peshawar, Pakistan.

Laamia Altuf, Superior University Lahore Pakistan.

Department of Radiological Science & MIT, Superior University Lahore, Pakistan.

Saima Arshad, National Conservation Strategy Institute of Sciences Islamabad Pakistan.

Lecturer-Radiology - National Conservation Strategy Institute of Sciences Islamabad, Pakistan.

Iqra Mussarat, University of Lahore-Lahore Pakistan.

MSDU - University Institute of Radiological Science & MIT, University of Lahore-Lahore, Pakistan.

Sidra Ghazanfar, University of Lahore-Lahore Pakistan.

BSMUT - University Institute of Radiological Science & MIT, University of Lahore-Lahore, Pakistan.

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