Extended Balloon Inflation Technique for Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction during Stent Deployment

Main Article Content

Muhammad Rafeeq Shah
Khalid Naseeb
Muhammad Nauman Khan
Asif Hussain
Tahir Saghir


Background: Primary percutaneous coronary intervention (PPCI) is the preferred method for treating ST-segment elevation myocardial infarction (STEMI), but the no-reflow phenomenon remains a significant challenge. This study investigates the efficacy of prolonged balloon inflation during stent deployment to reduce the incidence of no-reflow.

Objective: To assess whether extending the duration of balloon inflation during stent deployment in PPCI reduces the incidence of the no-reflow phenomenon compared to the conventional rapid inflation and deflation strategy.

Methods: This randomized controlled trial enrolled 122 patients at the National Institute of Cardiovascular Diseases, Pakistan, from February 2023 to January 2024. Patients were randomly assigned to either prolonged balloon inflation (PBSG) or conventional deployment (CDSG).

Results: The mean age in the PBSG was 59.83±10.10 years, and in the CDSG, it was 60.39±10.16 years. Male participants comprised 51.6%. The PBSG showed significantly lower immediate TIMI flow grades less than 3 (4.9% vs. 26.2%, P = 0.00), no-reflow incidence (0% vs. 26.2%, P = 0.00), corrected TIMI frame counts (36.96±4.25 vs. 46.13±6.82, P = 0.00), and higher ST-segment resolution ≥50% (77.0% vs. 57.4%, P = 0.02). Additionally, 59.0% in the PBSG achieved an MBG of 3 compared to 16.4% in the CDSG (P = 0.00).

Conclusion: Prolonged balloon inflation during stent deployment in PPCI significantly reduces the no-reflow phenomenon and improves myocardial perfusion in patients with STEMI.

Article Details

How to Cite
Shah, M. R., Khalid Naseeb, Muhammad Nauman Khan, Asif Hussain, & Tahir Saghir. (2024). Extended Balloon Inflation Technique for Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction during Stent Deployment. Journal of Health and Rehabilitation Research, 4(2), 847–853. https://doi.org/10.61919/jhrr.v4i2.965
Author Biographies

Muhammad Rafeeq Shah, NICVD - Karachi - Pakistan.

MBBS - FCPS (Adult Cardiology) - Post fellowship (Intervention Cardiology) - NICVD - Karachi - Pakistan.

Khalid Naseeb, NICVD - Pakistan.

Associate Professor - NICVD - Pakistan.

Muhammad Nauman Khan, NICVD - Pakistan.

Associate Professor - NICVD - Pakistan.

Asif Hussain, NICVD - Pakistan.

IVF - NICVD - Pakistan.

Tahir Saghir, NICVD - Pakistan.

Professor - NICVD - Pakistan.


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