Detection of Early Gastric Cancer and Lesion Segmentation Based on Deep Learning
DOI:
https://doi.org/10.61919/jhrr.v4i2.984Keywords:
Deep Learning, Early Gastric Cancer, Endoscopic Imaging, Lesion Segmentation, Medical ImagingAbstract
Background: Early detection and precise identification of gastric cancer tumors significantly enhance patient outcomes. Conventional methods often rely on manual interpretation of endoscopic images, which can be time-consuming and subjective. Recent advancements in deep learning offer promising alternatives for automating and improving these diagnostic processes.
Objective: The primary objective of this study is to explore the effectiveness of a deep learning model in detecting early gastric cancer and segmenting lesions from endoscopic images.
Methods: This retrospective study was conducted at Khalifa Gul Nawaz Teaching Hospital /BMC Bannu, from December 2021 to November 2022. Medical records and endoscopic images from 180 patients with suspected or confirmed gastric lesions were analyzed. Images were diversified in terms of lesion types and characteristics. Preprocessing steps including standardization and enhancement techniques were applied to improve image quality for analysis.
Results: The deep learning model achieved an accuracy of 90% in identifying gastric cancer lesions, with a sensitivity of 85% and specificity of 92%. The area under the curve (AUC-ROC) was calculated to be 0.61, indicating a good discriminative performance of the model.
Conclusion: The deep learning model demonstrated significant potential for enhancing the detection and segmentation of early gastric cancer from endoscopic images, providing a valuable tool for gastroenterologists in the early diagnosis and treatment planning.
Downloads
References
Zhang K, Wang H, Cheng Y, Liu H, Gong Q, Zeng Q, Zhang T, Wei G, Wei Z, Chen D. Early gastric cancer detection and lesion segmentation based on deep learning and gastroscopic images. Sci Rep. 2024 Apr 3;14(1):7847. doi: 10.1038/s41598-024-58361-8. Erratum in: Sci Rep. 2024 Apr 19;14(1):9025. PMID: 38570595; PMCID: PMC10991264.
Sumiyama K. Past and current trends in endoscopic diagnosis for early stage gastric cancer in Japan. Gastric Cancer. 2017;20(Suppl 1):20–27. doi: 10.1007/s10120-016-0659-4.
Jin Z, Gan T, Wang P, Fu Z, Zhang C, Yan Q, et al. Deep learning for gastroscopic images: Computer-aided techniques for clinicians. Biomed. Eng. Online. 2022;21(1):12. doi: 10.1186/s12938-022-00979-8.
Ishioka M, Hirasawa T, Tada T. Detecting gastric cancer from video images using convolutional neural networks. Digest. Endosc. 2018;31(2):13306.
Ueyama H, Kato Y, Akazawa Y, Yatagai N, Komori H, Takeda T, et al. Application of artificial intelligence using a convolutional neural network for diagnosis of early gastric cancer based on magnifying endoscopy with narrow-band imaging. J. Gastroen. Hepatol. 2021;36(2):482–489. doi: 10.1111/jgh.15190.
Oura H, Matsumura T, Fujie M, Ishikawa T, Nagashima A, Shiratori W, et al. Development and evaluation of a double-check support system using artificial intelligence in endoscopic screening for gastric cancer. Gastric Cancer. 2022;25(2):392–400. doi: 10.1007/s10120-021-01256-8.
He K, Gkioxari G, Dollar P, Girshick R. Mask R-CNN. IEEE Trans. Pattern. Anal. 2020;42(2):386–397. doi: 10.1109/TPAMI.2018.2844175.
Hu J, Shen L, Albanie S, Sun G, Wu E. Squeeze-and-excitation networks. IEEE Trans. Pattern. Anal. 2020;42(8):2011–2023. doi: 10.1109/TPAMI.2019.2913372.
Almahairi A, Ballas N, Cooijmans T, Zheng Y, Larochelle H, Courville A. Dynamic capacity networks. Int. Conf. Mach. Learn. 2015;2015:2549–2558.
Pogorelov K, Randel K, Griwodz C, Eskeland S, de Lange T, Johansen D, et al. KVASIR: A multi-class image dataset for computer aided gastrointestinal disease detection. ACM. 2017;2017:164–169.
Wang S, Chen Y, Yi S, Chao G. Frobenius norm-regularized robust graph learning for multi-view subspace clustering. Appl. Intell. 2022;52(13):14935–14948. doi: 10.1007/s10489-022-03816-6.
Chao G, Wang S, Yang S, Li C, Chu D. Incomplete multi-view clustering with multiple imputation and ensemble clustering. Appl. Intell. 2022;52(13):14811–14821. doi: 10.1007/s10489-021-02978-z.
Shibata, T., Teramoto, A., Yamada, H., Ohmiya, N., Saito, K., & Fujita, H. (2019). Automated Detection and Segmentation of Early Gastric Cancer from Endoscopic Images Using Mask R-CNN. Applied Sciences, 10(11), 3842. https://doi.org/10.3390/app10113842
Zhou, X.; Takayama, R.; Wang, S.; Hara, T.; Fujita, H. Deep learning of the sectional appearances of 3D CT images for anatomical structure segmentation based on an FCN voting method. Med. Phys. 2017, 44, 5221–5233.
Sakai, Y.; Takemoto, S.; Hori, K.; Nishimura, M.; Ikematsu, H.; Yano, T.; Yokota, H. Automatic detection of early gastric cancer in endoscopic images using a transferring convolutional neural network. In Proceedings of the 40th International Conference of the IEEE Engineering in Medicine and Biology Society, Honolulu, HI, USA, 17–21 July 2018; pp. 4138–4141.
Yoon, H.J.; Kim, S.; Kim, J.-H.; Keum, J.-S.; Oh, S.-I.; Jo, J.; Chun, J.; Youn, Y.H.; Park, H.; Kwon, I.G.; et al. A lesion-based convolutional neural network improves endoscopic detection and depth prediction of early gastric cancer. J. Clin. Med. 2019, 8, 1310.
Teramoto, A.; Yamada, A.; Kiriyama, Y.; Tsukamoto, T.; Yan, K.; Zhang, L.; Imaizumi, K.; Saito, K.; Fujita, H. Automated classification of benign and malignant cells from lung cytological images using deep convolutional neural network. Inform. Med. Unlocked 2019, 16, 100205
He, K.; Zhang, X.; Ren, S.; Sun, J. Deep residual learning for image recognition. In Proceedings of the 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Las Vegas, NV, USA, 27–30 June 2016; pp. 770–778.
Shibata T, Teramoto A, Yamada H, Ohmiya N, Saito K, Fujita H. Automated detection and segmentation of early gastric cancer from endoscopic images using mask R-CNN. Applied Sciences. 2020 May 31;10(11):3842.
Siripoppohn V, Pittayanon R, Tiankanon K, Faknak N, Sanpavat A, Klaikaew N, Vateekul P, Rerknimitr R. Real-time semantic segmentation of gastric intestinal metaplasia using a deep learning approach. Clinical Endoscopy. 2022 May;55(3):390.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Rahid Gul, Muhammad Imran Farid, Sadaqat Ali, Muhammad Amjad Khan, Noor Sardar, Intikhab Alam, Nusrum Iqbal, Younas Ahmad
This work is licensed under a Creative Commons Attribution 4.0 International License.