Assessment of Hematological Parameters in Mycobacterium Tuberculosis-Infected Patients at Hayatabad Medical Complex, Peshawar, Pakistan Hematological Profile in TB Patients
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Abstract
Background: Mycobacterium tuberculosis is a major causative agent of pulmonary tuberculosis, significantly contributing to morbidity and mortality worldwide. In South Asia, including Pakistan, TB remains a primary cause of prolonged hospital stays and economic burden. It primarily affects the lungs and can alter various hematological parameters.
Objective: To assess the prevalence and characterize the hematological features of pulmonary tuberculosis patients at Hayat Abad Medical Complex, Peshawar, Pakistan.
Methods: A descriptive cross-sectional study was conducted from April to August 2024. A total of 220 sputum samples were collected from male and female patients of all ages with suspected TB. TB was confirmed in 31 patients using TB PCR. Hematological parameters, including WBC, RBC, Hb, HCT, MCV, MCH, and platelets, were analyzed using a Sysmex hematology analyzer. Data were analyzed using SPSS version 25.
Results: The prevalence of TB was 14% (31/220). All confirmed TB patients had elevated WBC and neutrophil counts (100%), decreased Hb and HCT (100%), and reduced MCV (96%). Lymphopenia was present in 90% of the cases.
Conclusion: Hematological deviations can be cost-effective markers for early TB diagnosis in resource-limited settings.
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