Prevalence and Antibiotic Susceptibility Pattern of Pseudomonas Aeruginosa from the Foot Ulcer of Diabetic Patients in Hayatabad Medical Complex Peshawar, Pakistan

Main Article Content

Muhammad Qasim
Arbab Haroon
Mehboob Ullah
Noora Amir
Huma Imtiaz
Tanveer Tara
Farah Shireen
Nabila Qayum
Muhammad Jawad Ullah
Inam Ullah


Background: Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus, affecting 15% of diabetic patients and often leading to severe outcomes like amputation. These ulcers frequently become infected with bacteria such as Pseudomonas aeruginosa, which is known for its robust antibiotic resistance.

Objective: To investigate the prevalence and antibiotic susceptibility patterns of Pseudomonas aeruginosa isolated from the foot ulcers of diabetic patients in Hayatabad Medical Complex, Peshawar.

Methods: A total of 103 clinical samples from diabetic foot ulcers were collected and analyzed for the presence of Pseudomonas aeruginosa using culture techniques and biochemical tests. The antibiotic susceptibility was assessed using the Kirby-Bauer disk diffusion method to identify effective treatments.

Results: Pseudomonas aeruginosa was identified in 48 (46.60%) of the samples. High resistance was noted against amoxicillin-clavulanic acid (100%), and notable sensitivity was observed to gentamicin (79.16%) and cefoperazone-sulbactam (87.5%). The susceptibility to other tested antibiotics varied, with moderate resistance seen in agents like cefotaxime (25%) and trimethoprim-sulfamethoxazole (33.33%).

Conclusion: The study highlights a significant presence of Pseudomonas aeruginosa in diabetic foot ulcers with substantial antibiotic resistance, emphasizing the need for precise susceptibility testing to guide effective treatment strategies.

Article Details

How to Cite
Muhammad Qasim, Arbab Haroon, Mehboob Ullah, Noora Amir, Huma Imtiaz, Tanveer Tara, Farah Shireen, Nabila Qayum, Muhammad Jawad Ullah, & Inam Ullah. (2024). Prevalence and Antibiotic Susceptibility Pattern of Pseudomonas Aeruginosa from the Foot Ulcer of Diabetic Patients in Hayatabad Medical Complex Peshawar, Pakistan. Journal of Health and Rehabilitation Research, 4(2), 414–420.
Author Biographies

Muhammad Qasim, City University of Science and Information Technology- Peshawar- Pakistan

Department of Health Sciences, City University of Science and Information Technology- Peshawar- Pakistan

Arbab Haroon, Lawaghar Institute of Medical Sciences- Karak- Pakistan

Lawaghar Institute of Medical Sciences- Karak- Pakistan

Mehboob Ullah, University of Haripur- Haripur- Pakistan

Department of Microbiology- University of Haripur- Haripur- Pakistan

Noora Amir, University of Swat- Swat- Pakistan

Centre for Biotechnology and Microbiology- University of Swat- Swat- Pakistan

Huma Imtiaz, University of Peshawar- Peshawar- Pakistan

Center of Biotechnology and Microbiology- University of Peshawar- Peshawar- Pakistan

Tanveer Tara, National Skills University- Islamabad- Pakistan

Department of Health Sciences Technology- National Skills University- Islamabad- Pakistan

Farah Shireen, Iqra National University- Peshawar- Pakistan

Department of Allied Health Sciences- Iqra National University- Peshawar- Pakistan

Nabila Qayum, University of Swat- Swat- Pakistan

Centre for Biotechnology and Microbiology- University of Swat- Swat- Pakistan

Muhammad Jawad Ullah, University of Peshawar- Peshawar- Pakistan-

Center of Biotechnology and Microbiology- University of Peshawar- Peshawar- Pakistan-

Inam Ullah, Iqra National University- Peshawar- Pakistan

Department of Allied Health Sciences- Iqra National University- Peshawar- Pakistan


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