Frequency of Perforated Appendix in Acute Appendicitis at BMC Hospital Quetta
DOI:
https://doi.org/10.61919/jhrr.v4i1.1764Keywords:
Perforated Appendicitis, Acute Abdomen, General Surgery, Surgical Complications, Peritonitis, Mortality, Morbidity.Abstract
Background: Perforated appendicitis remains a significant complication of acute appendicitis, contributing to increased morbidity and mortality, particularly in settings with delayed diagnosis. Despite advancements in surgical management, the incidence, risk factors, and outcomes of perforated appendicitis vary across populations, necessitating further investigation.
Objective: This study aimed to determine the frequency of perforated appendicitis among patients with acute appendicitis at BMC Hospital Quetta and evaluate the associated morbidity, mortality, and surgical outcomes.
Methods: This prospective observational study was conducted from October 19, 2023, to October 20, 2024, including 63 patients diagnosed intraoperatively with perforated appendicitis. Patients aged ≥12 years with confirmed perforation were included, while those with non-perforated appendicitis or appendicular mass were excluded. Data collection included clinical presentations, laboratory findings, intraoperative observations, and postoperative complications. Statistical analysis was performed using SPSS v27, with chi-square tests for categorical variables and logistic regression to assess risk factors. Ethical approval was obtained, and informed consent was secured.
Results: The perforation rate was 13.8%, with the highest prevalence in the 21–30-year age group (31.8%). The complication rate was 72.2%, and mortality was 4.8%, with severe peritoneal contamination (>150 ml) increasing mortality risk to 54.5%. Late presentation significantly correlated with adverse outcomes (p<0.05).
Conclusion: Delayed presentation and severe peritoneal contamination are key predictors of morbidity and mortality in perforated appendicitis. Early diagnosis and timely surgical intervention are essential to improving patient outcomes.
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Copyright (c) 2024 Muhammad Riaz, Ahmad Shah, Zahid Saeed, Nazeer Ahmed Sasoli, Ghulam Mustafa, Bilal Masood, Meharullah Kasi

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