THE EFFECT OF O-3FA NUTRITIONAL SUPPLEMENT ON PRIMARY DYSMENORRHEA: A RANDOMIZED CONTROLLED TRIAL
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Abstract
Background: Primary dysmenorrhea is a prevalent gynaecological condition that affects many females and is also referred to as menstruation cramps. Because of its anti-inflammatory quality, O-3FAs (OFA) supplementation has been recommended as a possible alternative to pharmaceutical therapy for primary dysmenorrhea.
Objective: The objective was to determine the OFA supplementation effect on menstrual pain severity and menstrual cycle duration in women with primary dysmenorrhea.
Methods: A randomised controlled trial was conducted at five major universities/Colleges lasted for a total of six months. A randomization procedure was used to determine whether treatment, OFA supplementation or a placebo, each of 48 primary dysmenorrheic women aged 24 to 40 would receive. A visual analogue scale (VAS) and a calendar approach were used, respectively, to determine the level of menstrual discomfort and the duration of the menstrual cycle at both the beginning of the study and after the intervention.
Results: The mean menstrual pain severity in the intervention group decreased significantly from 7.2 ± 1.1 at baseline to 4.5 ± 1.3 post-intervention, whereas the mean menstrual pain severity in the control group remained relatively unchanged from baseline (7.4 ± 1.2) to post-intervention (6.9 ± 1.1). The mean menstrual cycle duration in the intervention group decreased from 28.4 ± 2.1 days at baseline to 4.8 ± 0.7 days post-intervention, but the difference observed in two groups was not significant. The baseline characteristics of the intervention and control groups were similar, indicating effective randomization.
Conclusion: OFA supplement found to be an effective non-pharmaceutical therapy for primary dysmenorrhea, since it significantly lowers the degree of menstrual discomfort compared to placebo.
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References
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