Association Between Pain and Radiological Changes in Patients with Knee Osteoarthritis

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Asma Munawar
Muhammad Mahmood Alam Durrani
M. Waseem Akhtar
Mubashar Ali
Adeela Shafqat
Saiem Alam
Mohammad Hannan Zahid
Amna Munawar


Background: Knee osteoarthritis (OA) is a leading cause of disability worldwide, characterized by joint degeneration, pain, and functional limitations. Despite the prevalence of knee OA, the relationship between radiographic changes and the severity of pain remains complex. Previous studies have offered conflicting views on the association between structural joint alterations and clinical symptoms.

Objective: The aim of this study was to investigate the association between radiographic degenerative changes in the knee, as classified by the Kellgren and Lawrence grading system, and the severity of resting pain measured using the Numeric Pain Rating Scale (NPRS).

Methods: This cross-sectional study was conducted on 70 patients diagnosed with knee OA at multiple healthcare facilities in Lahore, Pakistan, from July 2022 to January 2023. Participants aged between 40 and 80 years, both males and females, were included. The severity of knee OA was determined using the Kellgren-Lawrence grading system through X-ray evaluations. Pain severity was assessed using the NPRS. Data were analyzed using SPSS version 25.0, with chi-square tests applied to explore the association between radiographic grades of knee OA and pain severity.

Results: The distribution of knee OA severity among participants was as follows: Grade I (22.9%), Grade II (25.7%), Grade III (32.9%), and Grade IV (18.6%). Pain severity reported by participants was predominantly mild (55.7%), followed by moderate (37.1%) and severe (7.1%). Statistical analysis revealed a significant association between the grade of knee OA and the severity of resting pain (Chi-square = 30.06, p < 0.0001), indicating that higher grades of knee OA were correlated with increased pain severity.

Conclusion: The study confirmed a significant association between radiographic degenerative changes in knee OA and the severity of resting pain. These findings suggest the need for comprehensive clinical assessments in patients with knee OA, incorporating both radiographic evaluations and pain severity measures to guide management and treatment strategies.

Article Details

How to Cite
Munawar, A., Durrani, M. M. A., Akhtar, M. W., Ali, M., Shafqat, A., Alam, S., Zahid, M. H., & Munawar , A. (2024). Association Between Pain and Radiological Changes in Patients with Knee Osteoarthritis . Journal of Health and Rehabilitation Research, 4(1), 608–612.
Author Biographies

Asma Munawar, Akhtar Saeed Medical and Dental College Lahore Pakistan.

Physical Therapist, Akhtar Saeed College of Rehabilitation Sciences.

Muhammad Mahmood Alam Durrani, Akhtar Saeed Medical and Dental College Lahore Pakistan.

Physical Therapist, Principal, Akhtar Saeed College of Rehabilitation Sciences.

M. Waseem Akhtar, Akhtar Saeed Medical and Dental College Lahore Pakistan.

Physical Therapist, Head of Department, Akhtar Saeed College of Rehabilitation Sciences.

Mubashar Ali, Akhtar Saeed Medical and Dental College Lahore Pakistan.

Physical Therapist, Akhtar Saeed College of Rehabilitation Sciences.

Adeela Shafqat, Akhtar Saeed Medical and Dental College Lahore Pakistan.

Physical Therapist, Akhtar Saeed College of Rehabilitation Sciences.

Saiem Alam, Farooq Hospital Lahore Pakistan.

Physical Therapist.


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