Unveiling the Spectrum of Megaloblastic Anemia: Insights from a Multifaceted Study at Abbas Institute of Medical Sciences, Muzaffarabad

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Published: Dec 13, 2023
DOI: https://doi.org/10.61919/jhrr.v3i2.190
Keywords:
Megaloblastic anemia, Pathology, EDTA, Case control study

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Abdul Mannan Kiani
Abbas Institute of Medical Sciences- Muzaffarabad
Allah Dad Khan
Institute of Health Sciences-Hazara Campus
Nabeel Saeed
Comsats University Islamabad
Syed Sohail Ahmad
Khyber Pakhtunkhwa Institute of Medical Sciences- Peshawar
Wali Khan
Médecins Sans Frontières Operational Centre Amsterdam-Chaman-project-Balochistan
Raja Waseem
Health Services Academy- Islamabad
Farukh Javaid
Comsats University Islamabad

Abstract

Background: This study aimed to determine the frequency of Megaloblastic Anemia cases presenting in the outpatient department (OPD) and wards of AIMS Hospital in Muzaffarabad, AJ&K.


Methods: Conducted at the Pathology department of Abbas Institute of Medical Sciences from May 2022 to October 2022, this case-control study analyzed 125 cases from OPD and wards. Patient interviews, venous blood sample collection, and complete blood picture (CP) analysis, including peripheral film (PF) tests and Vitamin B12 and folates levels reports, were conducted using a Hematology analyzer. Statistical analysis using SPSS version 25.0 was employed.


Results: Statistical analysis revealed a mean age of 3.656, with females having a higher frequency of Megaloblastic Anemia, especially during childbearing age. Males had a higher frequency in children and the elderly. The residential distribution showed a balance of village and city dwellers, whereas the patient category breakdown showed a higher frequency in the young age group.


Conclusion: The study highlighted Megaloblastic Anemia's serious public health significance, its causes, and the observed trends in the study population. Surgical interventions, particularly abdominal surgeries, were identified as potential contributors. Analyses of peripheral smears revealed varying degrees of anemia severity, with most cases being moderate. The study concluded that Megaloblastic Anemia is more common in females, especially during childbearing age, and in males, especially in children and the elderly. These findings highlight the importance of targeted interventions and nutritional education programs in addressing the specific demographic trends observed in this study population.

Article Details

How to Cite
Mannan Kiani, A., Dad Khan, A., Saeed, N., Sohail Ahmad, S., Khan, W., Waseem, R., & Javaid, F. (2023). Unveiling the Spectrum of Megaloblastic Anemia: Insights from a Multifaceted Study at Abbas Institute of Medical Sciences, Muzaffarabad. Journal of Health and Rehabilitation Research, 3(2), 500–505. https://doi.org/10.61919/jhrr.v3i2.190
Issue
Vol. 3 No. 2 (2023): Volume 3, Issue 2 - July to December 2023
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Abdul Mannan Kiani, Abbas Institute of Medical Sciences- Muzaffarabad

Pathology Department

Allah Dad Khan, Institute of Health Sciences-Hazara Campus

Department of Medical Laboratory Technology

Syed Sohail Ahmad, Khyber Pakhtunkhwa Institute of Medical Sciences- Peshawar

Lecturer at Department of Medical Laboratory Technology

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