THE ROLE OF NON-INVASIVE BRAIN STIMULATION ON PHYSICAL FUNCTION AND QUALITY OF LIFE PATIENTS AFTER STROKE.
Main Article Content
Abstract
Background
Non-invasive brain stimulation, which has emerged as a successful additional treatment for the physical rehabilitation of stroke patients, includes a number of different types of stimulation, two of which are transcranial direct current and magnetic stimulation. Regrettably, research on the effect of NIBS on the quality of life and physical function among stroke survivors has shown conflicting results.
Objective
Aim of the current systematic review was to evaluate the impact of NIB stimulation on quality of life and physical functioning among the stroke survivors.
Materials & Methods
A comprehensive search of research databases was carried out in order to locate clinical trials that investigated the impact of NIBS on the physical function of stroke survivors as well as the quality of their life. Cochrane risk-of-bias (RoB 2) tool was used for quality assessment and to detect level of bias while ROBINS-I which was discover in non-randomised studies of interventions tool was used for studies which were not fully clinical trials. a matter analysis was also performed to detect standard mean difference far motor function and quality of life.
Results
there were identified total of 23 studies to include in this review. It was saying that NIBS showed significantly positive affect on physical function Vida standard mean difference of 0.46 and quality of life having standard mean defence of 0.39. Subgroup analysis conducted between acute subacute or chronic patients showed no significant difference.
Conclusion
According to the findings of the study, tDCS and TMS both modalities have a positive effective influence on the rehabilitation process after a stroke in terms of the improvement of a patient's physical function and their overall quality of life. However, Further research is required to define parameters such as dosage, type of modality, and follow up effect of NIBS on post stroke survivors.
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References
Santana K, França E, Sato J, Silva A, Queiroz M, de Farias J, et al. Non-invasive brain stimulation for fatigue in post-acute sequelae of SARS-CoV-2 (PASC). Brain Stimulation. 2023;16(1):100-7.
Hara T, Shanmugalingam A, McIntyre A, Burhan AM. The effect of non-invasive brain stimulation (NIBS) on executive functioning, attention and memory in rehabilitation patients with traumatic brain injury: A systematic review. Diagnostics. 2021;11(4):627.
Ahorsu DK, Adjaottor ES, Lam BYH. Intervention effect of non-invasive brain stimulation on cognitive functions among people with traumatic brain injury: A systematic review and meta-analysis. Brain sciences. 2021;11(7):840.
Parikh V, Medley A, Chung Y-C, Goh H-T. Optimal timing and neural loci: a scoping review on the effect of non-invasive brain stimulation on post-stroke gait and balance recovery. Topics in Stroke Rehabilitation. 2023;30(1):84-100.
Mancuso V, Stramba-Badiale C, Cavedoni S, Pedroli E, Cipresso P, Riva G. Virtual reality meets non-invasive brain stimulation: integrating two methods for cognitive rehabilitation of mild cognitive impairment. Frontiers in Neurology. 2020;11:566731.
O'Brien A, Bertolucci F, Torrealba‐Acosta G, Huerta R, Fregni F, Thibaut A. Non‐invasive brain stimulation for fine motor improvement after stroke: a meta‐analysis. European journal of neurology. 2018;25(8):1017-26.
Abdullahi A, Wong TW, Van Criekinge T, Ng SS. Combination of Non-invasive Brain Stimulation and Constraint Induced Movement Therapy in patients with Stroke: A Systematic Review and Meta-analysis. Expert Review of Neurotherapeutics. 2023(just-accepted).
Draaisma LR, Wessel MJ, Hummel FC. Non-invasive brain stimulation to enhance cognitive rehabilitation after stroke. Neuroscience letters. 2020;719:133678.
Ghosh S. Improvement of gait and balance by non-invasive brain stimulation: its use in rehabilitation. Expert Review of Neurotherapeutics. 2019;19(2):133-44.
Veldema J, Gharabaghi A. Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke. Journal of NeuroEngineering and Rehabilitation. 2022;19(1):84.
Begemann MJ, Brand BA, Ćurčić-Blake B, Aleman A, Sommer IE. Efficacy of non-invasive brain stimulation on cognitive functioning in brain disorders: a meta-analysis. Psychological medicine. 2020;50(15):2465-86.
Ramger BC, Bader KA, Davies SP, Stewart DA, Ledbetter LS, Simon CB, et al. Effects of non-invasive brain stimulation on clinical pain intensity and experimental pain sensitivity among individuals with central post-stroke pain: a systematic review. Journal of Pain Research. 2019:3319-29.
Pipatsrisawat S, Klaphajone J, Kitisak K, Sungkarat S, Wivatvongvana P. Effects of combining two techniques of non-invasive brain stimulation in subacute stroke patients: a pilot study. BMC neurology. 2022;22(1):98.
A Garrido M, A Άlvarez E, L Acevedo F, I Moyano Á, P Castillo N, A Cavada G. Early non-invasive brain stimulation with modified constraint-induced movement therapy for motor and functional upper limb recovery in stroke patients: Study protocol. British Journal of Occupational Therapy. 2020;83(8):523-9.
Naro A, Calabrò RS. Improving Upper Limb and Gait Rehabilitation Outcomes in Post-Stroke Patients: A Scoping Review on the Additional Effects of Non-Invasive Brain Stimulation When Combined with Robot-Aided Rehabilitation. Brain Sciences. 2022;12(11):1511.
Linnhoff S, Koehler L, Haghikia A, Zaehle T. The therapeutic potential of non-invasive brain stimulation for the treatment of Long-COVID-related cognitive fatigue. Frontiers in Immunology. 2022;13.
Kuwahara W, Sasaki S, Yamamoto R, Kawakami M, Kaneko F. The effects of robot-assisted gait training combined with non-invasive brain stimulation on lower limb function in patients with stroke and spinal cord injury: A systematic review and meta-analysis. Frontiers in Human Neuroscience. 2022.
Ding X, Zhang S, Huang W, Zhang S, Zhang L, Hu J, et al. Comparative efficacy of non-invasive brain stimulation for post-stroke aphasia: a network meta-analysis and meta-regression of moderators. Neuroscience & Biobehavioral Reviews. 2022:104804.
da Silva TR, de Carvalho Nunes HR, Martins LG, da Costa RDM, de Souza JT, Winckler FC, et al. Non‐invasive Brain Stimulation Can Reduce Unilateral Spatial Neglect after Stroke: ELETRON Trial. Annals of Neurology. 2022;92(3):400-10.
Bressi F, Cinnera AM, Morone G, Campagnola B, Cricenti L, Santacaterina F, et al. Combining Robot-Assisted Gait Training and Non-Invasive Brain Stimulation in Chronic Stroke Patients: A Systematic Review. Frontiers in Neurology. 2022;13.
Balzan P, Tattersall C, Palmer R. Non-invasive brain stimulation for treating neurogenic dysarthria: A systematic review. Annals of Physical and Rehabilitation Medicine. 2022;65(5):101580.
Wessel MJ, Egger P, Hummel FC. Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls. Brain Stimulation. 2021;14(6):1456-66.
Potvin-Desrochers A, Paquette C. Potential non-invasive brain stimulation targets to alleviate freezing of gait in parkinson’s disease. Neuroscience. 2021;468:366-76.
Pastore-Wapp M, Nyffeler T, Nef T, Bohlhalter S, Vanbellingen T. Non-invasive brain stimulation in limb praxis and apraxia: A scoping review in healthy subjects and patients with stroke. Cortex. 2021;138:152-64.
Learmonth G, Benwell CS, Märker G, Dascalu D, Checketts M, Santosh C, et al. Non-invasive brain stimulation in Stroke patients (NIBS): A prospective randomized open blinded end-point (PROBE) feasibility trial using transcranial direct current stimulation (tDCS) in post-stroke hemispatial neglect. Neuropsychological Rehabilitation. 2021;31(8):1163-89.