Bacteriostatic Potential of Ginger, Garlic, and Fennel Seeds Against Helicobacter Pylori

Main Article Content

Muhammad Hamza
Zunaira Farooq
Iqra Rasheed
Hafiza Iqra Akram
Fahad Saad Alhodieb
Ghulam Fatima
Ayesha Khalid
Ezza Shafiq
Marriem Rafiq
Faiyaz Ahmed


Background: H. pylori infection is a global health concern associated with various gastrointestinal disorders. Conventional antibiotic treatments face challenges and side effects like antibiotic resistance, leads toward the exploration of alternative therapeutic options with minimum or no side effects.

Objective: This review explores the bacteriostatic potential of natural remedies, specifically ginger (Zingiber officinale), garlic (Allium sativum), and fennel seeds (Foeniculum vulgare), against Helicobacter pylori (H. pylori).

Methods: A comprehensive search was conducted in order to identify relevant studies investigating the impact of ginger, garlic, and fennel seeds on Helicobacter pylori. Databases including PubMed, and Google Scholar were systematically queried to ensure the therapeutic potential of ginger, garlic and fennel seeds against Helicobacter pylori.

Results: Ginger, with its bioactive compounds such as gingerol and shogaol, exhibits inhibitory effects on H. pylori growth through anti-adhesive, antibacterial, and immunomodulatory mechanisms. Garlic, rich in allicin and other active components, demonstrates antibacterial properties against H. pylori, showing promising effect in both preclinical and clinical studies. Fennel seeds, traditionally recognized for culinary purposes, reveal antimicrobial potential against H. pylori.

Conclusion: This review highlights the bacteriostatic potential of ginger, garlic, and fennel seeds against H. pylori. Comparative analysis suggests potential therapeutic effects, while methodological considerations and challenges indicate avenues for future research. The integration of natural remedies with conventional approaches may present novel strategies for H. pylori management.

Article Details

How to Cite
Hamza, M., Farooq, Z., Rasheed, I., Akram, H. I., Alhodieb, F. S., Fatima, G., Khalid, A., Shafiq, E., Rafiq, M., & Ahmed, F. (2024). Bacteriostatic Potential of Ginger, Garlic, and Fennel Seeds Against Helicobacter Pylori. Journal of Health and Rehabilitation Research, 4(1), 12–18.
Author Biographies

Muhammad Hamza, Government College University Faisalabad-38000 Punjab Pakistan.

Department of Nutritional Sciences.

Zunaira Farooq, Government College University Faisalabad-38000 Punjab Pakistan.

Department of Nutritional Sciences.

Iqra Rasheed, The University of Lahore UOL-55150 Pakistan.

University Institute of Diet and Nutritional Sciences UIDNS.

Hafiza Iqra Akram, Government College University Faisalabad-38000 Punjab Pakistan.

Department of Nutritional Sciences.

Fahad Saad Alhodieb, Qassim University-Ar Rass-51921 Saudi Arabia.

Department of Clinical Nutrition, College of Applied Health Sciences.

Ghulam Fatima, Ghazi University-Dera Ghazi Khan-32200 Pakistan.

Department of Zoology.

Ayesha Khalid, The University of Lahore UOL-55150 Pakistan.

University Institute of Diet and Nutritional Sciences UIDNS.

Ezza Shafiq, Khawaja Fareed University of Engineering and Information Technology Rahimyar Khan-64350 Pakistan.

Institute of Food Science and Technology.

Marriem Rafiq, Ghazi University-Dera Ghazi Khan-32200 Pakistan.

Department of Zoology.

Faiyaz Ahmed, Qassim University-Ar Rass-51921 Saudi Arabia.

Department of Clinical Nutrition, College of Applied Health Sciences.


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