Prevalence of Diabetes Mellitus and Chronic Complications of Diabetes Mellitus in District Buner Khyber Pakhtunkhwa, Pakistan
DOI:
https://doi.org/10.61919/jhrr.v4i1.413Keywords:
Diabetes Mellitus, Prevalence, Chronic Complications, Buner District, Khyber Pakhtunkhwa, Pakistan, Public HealthAbstract
Background: Diabetes Mellitus (DM) is a significant global public health concern, particularly in developing countries like Pakistan. The Buner District of Khyber Pakhtunkhwa, Pakistan, presents a unique demographic and geographical setting for studying the prevalence and chronic complications of DM.
Objective: This study aimed to assess the prevalence of diabetes mellitus and its chronic complications in the Buner District, Khyber Pakhtunkhwa, Pakistan, and to understand the demographic distribution of the disease.
Methods: A comprehensive, area-specific study was conducted from March 2022 to August 2022, involving 753 patients across eight localities in the Buner District. Data were collected using questionnaires, interviews, and observations at various medical centers. Participants included individuals from both rural and urban areas, with a demographic split of 486 males (64.54%) and 267 females (35.45%). The study also investigated six types of chronic complications associated with DM. Data analysis was performed using Microsoft Excel 2016 and SPSS version 25.
Results: The study found that the prevalence of diabetes mellitus in the Buner District was significantly high, with a higher incidence in urban areas compared to rural ones. The prevalence of chronic complications of DM varied, with cardiovascular conditions being the most prominent, followed by neuropathy, nephropathy, ocular conditions, and foot diseases.
Conclusion: The study highlights a high prevalence of diabetes mellitus and its chronic complications in the Buner District, with urban areas showing a higher incidence. The findings underscore the need for targeted healthcare strategies and interventions in this region to address the growing burden of DM.
Downloads
References
Ismail MYM, Yaheya M. Clinical evaluation of antidiabetic activity of Trigonella seeds and Aegle marmelos leaves. World Applied Sciences Journal. 2009;7(10):1231-4.
Azeem S, Khan U, Liaquat A. The increasing rate of diabetes in Pakistan: A silent killer. Annals of Medicine and Surgery. 2022;79.
Mukhtar Y, Galalain A, Yunusa U. A modern overview on diabetes mellitus: a chronic endocrine disorder. European Journal of Biology. 2020;5(2):1-14.
Redondo MJ, Hagopian WA, Oram R, Steck AK, Vehik K, Weedon M, et al. The clinical consequences of heterogeneity within and between different diabetes types. Diabetologia. 2020;63:2040-8.
Qidwai W, Ashfaq T. Imminent epidemic of diabetes mellitus in Pakistan: issues and challenges for health care providers. 2010.
Arora S, Ojha SK, Vohora D. Characterisation of streptozotocin induced diabetes mellitus in swiss albino mice. Global Journal of Pharmacology. 2009;3(2):81-4.
Olokoba AB, Obateru OA, Olokoba LB. Type 2 diabetes mellitus: a review of current trends. Oman medical journal. 2012;27(4):269.
Zimmet P, Alberti K, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414(6865):782-7.
Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes care. 2004;27(5):1047-53.
Abdullah S, Sarwar N, Khan MB, Khan FU, Afridi M. DETERMINANTS OF POOR ADHERENCE TO ANTIDIABETIC MEDICINE AMONG ADULT PATIENTS OF TYPE 2 DIABETES MELLITUS IN DISTRICT PESHAWAR, PAKISTAN: A CROSS-SECTIONAL STUDY.
Magliano DJ, Sacre JW, Harding JL, Gregg EW, Zimmet PZ, Shaw JE. Young-onset type 2 diabetes mellitus—Implications for morbidity and mortality. Nature Reviews Endocrinology. 2020;16(6):321-31.
Mekala KC, Bertoni AG. Epidemiology of diabetes mellitus. Transplantation, bioengineering, and regeneration of the endocrine pancreas: Elsevier; 2020. p. 49-58.
Metwally AA, Mehta P, Johnson BS, Nagarjuna A, Snyder MP. COVID-19–induced new-onset diabetes: trends and technologies. Diabetes. 2021;70(12):2733-44.
Akhtar N, Ilyas M, Muhammad K, Shams S, Saeed K, Asadullah A. Prevalence of Hepatitis C virus infections among the general population of Buner, Khyber Pakhtunkhwa, Pakistan. Biomedical Research and Therapy. 2016;3(12):1003-17.
Group TS. Long-term complications in youth-onset type 2 diabetes. New England Journal of Medicine. 2021;385(5):416-26.
Liu J, Ren Z-H, Qiang H, Wu J, Shen M, Zhang L, et al. Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention. BMC public health. 2020;20:1-12.
Lovic D, Piperidou A, Zografou I, Grassos H, Pittaras A, Manolis A. The growing epidemic of diabetes mellitus. Current vascular pharmacology. 2020;18(2):104-9.
Dżygało K, Nowaczyk J, Szwilling A, Kowalska A. Increased frequency of severe diabetic ketoacidosis at type 1 diabetes onset among children during COVID-19 pandemic lockdown: an observational cohort study. Pediatric Endocrinology Diabetes and Metabolism. 2020;26(4):167-75.
Faselis C, Katsimardou A, Imprialos K, Deligkaris P, Kallistratos M, Dimitriadis K. Microvascular complications of type 2 diabetes mellitus. Current vascular pharmacology. 2020;18(2):117-24.
Genco RJ, Graziani F, Hasturk H. Effects of periodontal disease on glycemic control, complications, and incidence of diabetes mellitus. Periodontology 2000. 2020;83(1):59-65.
Abdul Basit K, Fawwad A, Mustafa N, Davey T, Tahir B, Basit A. Changes in the prevalence of diabetes, prediabetes and associated risk factors in rural Baluchistan; a secondary analysis from repeated surveys (2002–2017). Plos one. 2023;18(4):e0284441.
Ahlqvist E, Prasad RB, Groop L. Subtypes of type 2 diabetes determined from clinical parameters. Diabetes. 2020;69(10):2086-93.
Alam S, Hasan MK, Neaz S, Hussain N, Hossain MF, Rahman T. Diabetes Mellitus: insights from epidemiology, biochemistry, risk factors, diagnosis, complications and comprehensive management. Diabetology. 2021;2(2):36-50.
Amidei CB, Fayosse A, Dumurgier J, Machado-Fragua MD, Tabak AG, van Sloten T, et al. Association between age at diabetes onset and subsequent risk of dementia. Jama. 2021;325(16):1640-9.
Bos M, Agyemang C. Prevalence and complications of diabetes mellitus in Northern Africa, a systematic review. BMC public health. 2013;13(1):1-7.
Bello-Chavolla OY, Bahena-López JP, Vargas-Vázquez A, Antonio-Villa NE, Márquez-Salinas A, Fermín-Martínez CA, et al. Clinical characterization of data-driven diabetes subgroups in Mexicans using a reproducible machine learning approach. BMJ Open Diabetes Research and Care. 2020;8(1):e001550.
Cloete L. Diabetes mellitus: an overview of the types, symptoms, complications and management. Nursing Standard (Royal College of Nursing (Great Britain): 1987). 2021;37(1):61-6.
Cole JB, Florez JC. Genetics of diabetes mellitus and diabetes complications. Nature reviews nephrology. 2020;16(7):377-90.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Imad Ali Khan, Samiyah Tasleem, Muhammad Razaq, Amina Rahat, Yasin Kayani, Tahir Azeem, Hasnain Zafar, Hameed Ur Rehman, Kausar Saeed
This work is licensed under a Creative Commons Attribution 4.0 International License.