Ultrasound Comparison of Renal Changes in Diabatic and Non-Diabatic Adult in Swabi
Main Article Content
Abstract
Background: Chronic kidney disease (CKD) is a major health concern globally, often leading to kidney failure, with diabetes and hypertension as significant risk factors. Early detection and effective management are crucial for mitigating its progression. Ultrasound imaging provides a non-invasive means to assess structural changes in the kidneys of both diabetic and non-diabetic individuals.
Objective: The objective of this study is to analyze renal changes in diabetic versus non-diabetic adults using ultrasound imaging to measure kidney dimensions, cortical thickness, and echogenicity grades, and to correlate these measurements with obesity, hypertension, and diabetes.
Methods: A cross-sectional study was conducted at Mahaban Medical and Research Hospital in Swabi, KP, Pakistan, including 65 adults aged 18-65. Kidney dimensions (length, width) and cortical thickness were measured using a Toshiba prime ultrasound machine with convex transducers ranging from 3.0—5.0 MHz to 7.0—14.0 MHz. Participants were categorized as diabetic or non-diabetic based on their medical records. Information on obesity, hypertension, and diabetes was collected through medical records and self-reporting. Echogenicity grades were assigned based on ultrasound findings, and data were analyzed using descriptive statistics and cross-tabulation of echogenicity grades.
Results: The study included 65 participants with a mean age of 42 years. The average dimensions for right kidneys were 9.14 cm in length, 3.98 cm in width, and cortical thickness of 0.80 cm; left kidneys measured 8.84 cm in length, 4.05 cm in width, and cortical thickness of 0.77 cm. Of the participants, 40% were obese, 63.1% had hypertension, and 44.6% were diagnosed with diabetes. The most common echogenicity grade observed was Grade 3, particularly in bilateral cases.
Conclusion: This study highlights the complex nature of kidney health, revealing significant impacts of obesity, hypertension, and diabetes on renal structure and function. The findings underscore the necessity for comprehensive clinical assessments and targeted interventions to prevent and manage CKD effectively.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Kramer HJ, Townsend RR, Griffin K, Flynn JT, Weiner DE, Rocco MV, Choi MJ, Weir MR, Chang TI, Agarwal R, Beddhu S. KDOQI US commentary on the 2017 ACC/AHA hypertension guideline. American Journal of Kidney Diseases. 2019 Apr 1;73(4):437-58.
Dekkers CC, Petrykiv S, Laverman GD, Cherney DZ, Gansevoort RT, Heerspink HJ. Effects of the SGLT‐2 inhibitor dapagliflozin on glomerular and tubular injury markers. Diabetes, Obesity and Metabolism. 2018;20(8):1988-93.
Bakr H. Punching shear of self-consolidated two-way slabs: Memorial University of Newfoundland; 2015.
Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas. Diabetes research and clinical practice. 2019;157:107843.
Wu W-Q, Wang Q, Fang Y, Shao Y, Tang S, Deng Y, et al. Molecular doping enabled scalable blading of efficient hole-transport-layer-free perovskite solar cells. Nature communications. 2018;9(1):1-8.
Perkovic V, Jardine MJ, Neal B, Bompoint S, Heerspink HJ, Charytan DM, et al. Canagliflozin and renal outcomes in type 2 diabetes and nephropathy. New England Journal of Medicine. 2019;380(24):2295-306.
Hussain N, Rigoni U, Orij RP. Corporate governance and sustainability performance: Analysis of triple bottom line performance. Journal of business ethics. 2018;149:411-32
Hussain A, Bhowmik B, do Vale Moreira NC. COVID-19 and diabetes: Knowledge in progress. Diabetes research and clinical practice. 2020;162:108142.
Bakris GL, Agarwal R, Anker SD, Pitt B, Ruilope LM, Rossing P, et al. Effect of finerenone on chronic kidney disease outcomes in type 2 diabetes. New England Journal of Medicine. 2020;383(23):2219-29.
Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of extracellular vesicles. 2018;7(1):1535750.
Kramer HJ, Townsend RR, Griffin K, Flynn JT, Weiner DE, Rocco MV, Choi MJ, Weir MR, Chang TI, Agarwal R, Beddhu S. KDOQI US commentary on the 2017 ACC/AHA hypertension guideline. American Journal of Kidney Diseases. 2019 Apr 1;73(4):437-58.
Dekkers CC, Petrykiv S, Laverman GD, Cherney DZ, Gansevoort RT, Heerspink HJ. Effects of the SGLT‐2 inhibitor dapagliflozin on glomerular and tubular injury markers. Diabetes, Obesity and Metabolism. 2018;20(8):1988-93.
Bakr H. Punching shear of self-consolidated two-way slabs: Memorial University of Newfoundland; 2015.
Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas. Diabetes research and clinical practice. 2019;157:107843.
Wu W-Q, Wang Q, Fang Y, Shao Y, Tang S, Deng Y, et al. Molecular doping enabled scalable blading of efficient hole-transport-layer-free perovskite solar cells. Nature communications. 2018;9(1):1-8.
Perkovic V, Jardine MJ, Neal B, Bompoint S, Heerspink HJ, Charytan DM, et al. Canagliflozin and renal outcomes in type 2 diabetes and nephropathy. New England Journal of Medicine. 2019;380(24):2295-306.
Hussain N, Rigoni U, Orij RP. Corporate governance and sustainability performance: Analysis of triple bottom line performance. Journal of business ethics. 2018;149:411-32.
Hussain A, Bhowmik B, do Vale Moreira NC. COVID-19 and diabetes: Knowledge in progress. Diabetes research and clinical practice. 2020;162:108142.
Sun Y, Ren Y, Lan P, Yu X, Feng J, Hao D, Xie L. Clinico-pathological features of diabetic and non-diabetic renal diseases in type 2 diabetic patients: a retrospective study from a 10-year experience in a single center. International Urology and Nephrology. 2023 Sep;55(9):2303-12.
Jung SI, Moon MH, Sung CK, Lee MS, Park JH, Oh S. Renal Doppler ultrasonography for predicting non-diabetic kidney disease in patients with diabetes. Ultrasonography. 2023 Jul;42(3):440.