Health Benefits of Physical Therapy Interventions in Children Suffering from Down Syndrome. A Systematic Review
DOI:
https://doi.org/10.61919/jhrr.v3i2.158Keywords:
Down syndrome, physical therapy, Rehabilitation, motor development, exercise intervention, systematic reviewAbstract
Background: Down syndrome is associated with a spectrum of physical and developmental challenges that can impact an individual's quality of life. Physical therapy interventions are commonly employed to address these challenges, aiming to improve physical fitness, strength, and achievement of developmental milestones. However, the extent of their effectiveness is not uniformly documented.
Objective: This systematic review sought to evaluate the comparative effectiveness of various physical therapy interventions versus no intervention or standard care in enhancing physical fitness, strength, and developmental milestones in individuals with Down syndrome.
Methods: Adhering to PRISMA guidelines, a comprehensive search of electronic databases including PubMed, MEDLINE, Cochrane Library, Embase, and Google Scholar was conducted for studies published between January 2000 and December 2022. RCTs and pre-post test studies in English that focused on physical therapy interventions for Down syndrome were included. The PEDro scale was utilized for quality assessment. Data synthesis provided a qualitative summary of the intervention outcomes.
Results: Nine studies met the inclusion criteria, with a total sample size of 327 individuals with Down syndrome. The review highlighted significant improvements in balance, muscle strength, motor skills, and cognitive function following various physical therapy interventions such as progressive resistance training, treadmill exercises, and the use of virtual reality. The duration of these interventions ranged from 6 weeks to 1 year, demonstrating both short- and long-term benefits.
Conclusion: The review substantiates that physical therapy interventions offer considerable benefits in improving the health and developmental outcomes for individuals with Down syndrome. These findings underscore the importance of integrating targeted physical therapy into standard care practices. Nevertheless, further research is warranted to explore the long-term impact and to develop optimal intervention strategies.
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Lin H-C, Wuang Y-P. Strength and agility training in adolescents with Down syndrome: A randomized controlled trial. Research in Developmental Disabilities. 2012;33(6):2236-44.
Alsakhawi RS, Elshafey MA. Effect of core stability exercises and treadmill training on balance in children with Down syndrome: randomized controlled trial. Advances in therapy. 2019;36:2364-73.
Foley C, Killeen OG. Musculoskeletal anomalies in children with Down syndrome: an observational study. Archives of disease in childhood. 2019;104(5):482-7.
Nixon DW. Down syndrome, obesity, alzheimer’s disease, and cancer: A brief review and hypothesis. Brain sciences. 2018;8(4):53.
Simpson R, Oyekan AA, Ehsan Z, Ingram DG. Obstructive sleep apnea in patients with Down syndrome: current perspectives. Nature and science of sleep. 2018:287-93.
Shields N, Taylor NF. A student-led progressive resistance training program increases lower limb muscle strength in adolescents with Down syndrome: a randomised controlled trial. Journal of physiotherapy. 2010;56(3):187-93.
Zhang L, Zhu X, Haegele JA, Wang D, Wu X. Health and fitness indicators of individuals with intellectual disabilities in China: Performance differences among disability levels. Journal of Intellectual & Developmental Disability. 2020;45(2):155-8.
Ballenger BK, Schultz EE, Dale M, Fernhall B, Motl RW, Agiovlasitis S. Health Outcomes of Physical Activity Interventions in Adults With Down Syndrome: A Systematic Review. Adapted physical activity quarterly : APAQ. 2023;40(2):378-402.
Ruiz‐González L, Lucena‐Antón D, Salazar A, Martín‐Valero R, Moral‐Munoz J. Physical therapy in Down syndrome: systematic review and meta‐analysis. Journal of Intellectual Disability Research. 2019;63(8):1041-67.
Paul Y, Ellapen TJ, Barnard M, Hammill HV, Swanepoel M. The health benefits of exercise therapy for patients with Down syndrome: A systematic review. African journal of disability. 2019;8:576.
Rodríguez-Grande E-I, Vargas-Pinilla O-C, Torres-Narvaez M-R, Rodríguez-Malagón N. Neuromuscular exercise in children with Down Syndrome: a systematic review. Scientific reports. 2022;12(1):14988.
Rodríguez-Grande E-I, Buitrago-López A, Torres-Narváez M-R, Serrano-Villar Y, Verdugo-Paiva F, Ávila C. Therapeutic exercise to improve motor function among children with Down Syndrome aged 0 to 3 years: a systematic literature review and meta‑analysis. Scientific reports. 2022;12(1):13051.
Sarkis-Onofre R, Catalá-López F, Aromataris E, Lockwood C. How to properly use the PRISMA Statement. Systematic reviews. 2021;10(1):1-3.
Selinger E, Neuenschwander M, Koller A, Gojda J, Kühn T, Schwingshackl L, et al. Evidence of a vegan diet for health benefits and risks–an umbrella review of meta-analyses of observational and clinical studies. Critical Reviews in Food Science and Nutrition. 2023;63(29):9926-36.
Patikorn C, Roubal K, Veettil SK, Chandran V, Pham T, Lee YY, et al. Intermittent fasting and obesity-related health outcomes: an umbrella review of meta-analyses of randomized clinical trials. JAMA network open. 2021;4(12):e2139558-e.
Krnic Martinic M, Pieper D, Glatt A, Puljak L. Definition of a systematic review used in overviews of systematic reviews, meta-epidemiological studies and textbooks. BMC medical research methodology. 2019;19:1-12.
Nazir S, Ali Y, Ullah N, García-Magariño I. Internet of things for healthcare using effects of mobile computing: a systematic literature review. Wireless Communications and Mobile Computing. 2019;2019:1-20.
Gusenbauer M, Haddaway NR. Which academic search systems are suitable for systematic reviews or meta‐analyses? Evaluating retrieval qualities of Google Scholar, PubMed, and 26 other resources. Research synthesis methods. 2020;11(2):181-217.
Moseley AM, Elkins MR, Van der Wees PJ, Pinheiro MB. Using research to guide practice: the physiotherapy evidence database (PEDro). Brazilian journal of physical therapy. 2020;24(5):384-91.
Marshall IJ, Wallace BC. Toward systematic review automation: a practical guide to using machine learning tools in research synthesis. Systematic reviews. 2019;8:1-10.
Novaes LF, Liu J, Shen Y, Lu L, Meinhardt JM, Lin S. Electrocatalysis as an enabling technology for organic synthesis. Chemical Society Reviews. 2021;50(14):7941-8002.
Shrestha B, Dunn L. The declaration of Helsinki on medical research involving human subjects: a review of seventh revision. Journal of Nepal Health Research Council. 2019;17(4):548-52.
Ptomey LT, Szabo AN, Willis EA, Gorczyca AM, Greene JL, Danon JC, et al. Changes in cognitive function after a 12-week exercise intervention in adults with Down syndrome. Disability and Health Journal. 2018;11(3):486-90.
Shields N, Taylor NF, Wee E, Wollersheim D, O'Shea SD, Fernhall B. A community-based strength training programme increases muscle strength and physical activity in young people with Down syndrome: A randomised controlled trial. Research in Developmental Disabilities. 2013;34(12):4385-94.
Gupta S, Rao Bk, Kumaran S. Effect of strength and balance training in children with Down’s syndrome: a randomized controlled trial. Clinical Rehabilitation. 2011;25(5):425-32.
Ulrich DA, Burghardt AR, Lloyd M, Tiernan C, Hornyak JE. Physical activity benefits of learning to ride a two-wheel bicycle for children with Down syndrome: A randomized trial. Physical therapy. 2011;91(10):1463-77.
Rahman SA, Rahman A. Efficacy of virtual reality-based therapy on balance in children with Down syndrome. World Applied Sciences Journal. 2010;10(3):254-61.
Looper J, Ulrich DA. Effect of treadmill training and supramalleolar orthosis use on motor skill development in infants with Down syndrome: a randomized clinical trial. Physical therapy. 2010;90(3):382-90.
Bruininks RH, Bruininks BD. Bruininks-Oseretsky test of motor proficiency. 1978.
Veldman SL, Santos R, Jones RA, Sousa-Sá E, Okely AD. Associations between gross motor skills and cognitive development in toddlers. Early human development. 2019;132:39-44.
Guízar-Sahagún G, Grijalva I, Franco-Bourland RE, Madrazo I. Aging with spinal cord injury: a narrative review of consequences and challenges. Ageing Research Reviews. 2023:102020.
Degtiar I, Rose S. A review of generalizability and transportability. Annual Review of Statistics and Its Application. 2023;10:501-24.
Luchini C, Veronese N, Nottegar A, Shin JI, Gentile G, Granziol U, et al. Assessing the quality of studies in meta‐research: Review/guidelines on the most important quality assessment tools. Pharmaceutical statistics. 2021;20(1):185-95.
Peter WF, Swart NM, Meerhoff GA, Vliet Vlieland TP. Clinical practice guideline for physical therapist management of people with rheumatoid arthritis. Physical therapy. 2021;101(8):pzab127.
Barton M, Guerrero K, Martinez A, Umagat A. The Effects of a Telehealth Exercise Intervention on Balance in Adults with Down Syndrome. 2022.
Ward KM, Wittekind SG, White DA. Pediatric Physical Activity Promotion, Exercise Therapy and Cardiac Rehabilitation. Pediatric Cardiology: Fetal, Pediatric, and Adult Congenital Heart Diseases: Springer; 2023. p. 1-31.
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Copyright (c) 2023 Sania Ahmad, Abdul Mannan , Aitzaz Azam, Seemab Arif, Mashar Hayat, Tahir Hafeez
This work is licensed under a Creative Commons Attribution 4.0 International License.
